Treatments | Subjects (n) | Responders/subjects (%) | RR [95%CI] | |
---|---|---|---|---|
Drug | Placebo | |||
Anticonvulsants [10 trials, 3 agents] | 1281 | 313/657 [47.6%] | 181/624 [29.0%] | 1.61 [1.39–1.87] |
Antidepressants [12 trials, 11 agents] | 1895 | 383/803 [48.9%] | 419/1092 [38.4%] | 1.32 [1.07–1.62] |
Antipsychotics [13 trials, 6 agents] | 6044 | 2135/3859 [55.3%] | 904/2185 [41.4%] | 1.28 [1.09–1.51] |
Lithium [1 trial, 1 agent] | 265 | 85/136 [62.5%] | 72/129 [55.8%] | 1.12 [0.92–1.37] |
Pooled/totals [36 trials, 21 agents] | 9485 | 2926/5455 [54.4%] | 1576/4030 [39.4%] | 1.37 [1.30–1.44] |