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Table 3 Case series of three BD patients with the minor G-allele of rs200044200

From: Mitochondrial genetic variants associated with bipolar disorder and Schizophrenia in a Japanese population

 

BD patient 1

BD patient 2

BD patient 3

Age (years)

48

58

44

Sex

female

male

male

Age at onset (years)

25

44

35

Duration of illness (years)

23

14

9

Family history

SZ (aunt)

Unspecified psychiatric disorder (brother)

ASD/ADHD (son), Dementia (father)

Types of BD

I

II

II

Developmental disorders

-

-

-

Years of education

14

12

16

Premorbid IQ

92

110

104

Present IQ

80

n.a.

n.a.

Present occupation

Support for continuous employment type A

Unemployed

Unemployed

Former occupation

Children’s nurse

Bus driver

Clerical work

Primary symptom

Mania

Depression

Depression

Psychotic episode

+

-

-

Rapid cycler

+

-

+

Present prescription (mg/day)

Aripiprazole 12 mg,

Zotepine 25 mg,

Biperiden 2 mg,

Clonazepam 2 mg,

Loflazepic acid 2 mg,

Flunitrazepam 4 mg,

Triazolam 0.25 mg,

Valproic acid 800 mg

Flunitrazepam 2 mg,

Lithium 400 mg

Quetiapine 100 mg,

Flunitrazepam 2 mg,

Zopiclone 7.5 mg,

Lithium 900 mg

  1. BD, bipolar disorder; ASD, autism spectrum disorder; ADHD, attention-deficit hyperactivity disorder