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Table 3 Predictors of lithium response according to multivariate logistic regression

From: Type of cycle, temperament and childhood trauma are associated with lithium response in patients with bipolar disorders

 

OR

95% CI

Wald

P

Lithium responders vs. Non-responders

Age

1.01

0.97–1.04

0.15

0.695

Gender

0.52

0.23–1.17

2.48

0.115

Diagnosis

2.35

0.90–6.15

3.01

0.083

Age at onset

0.96

0.91-1.00

3.36

0.067

Substance use

2.53

0.93–6.88

2.28

0.070

MDI cycle

3.47

1.61–7.50

10.01

0.002**

TEMPS-A-SF Hyperthymic

1.20

1.02–1.41

4.66

0.031*

TEMPS-A-SF Irritable

1.28

1.08–1.52

8.18

0.004**

CTQ-SF Emotional Abuse

0.87

0.76–0.98

4.95

0.026*

CTQ-SF Physical Abuse

0.83

0.70–0.98

4.57

0.033*

CTQ-SF Sexual Abuse

0.98

0.79–1.21

0.04

0.850

  1. *p < 0.05; **p < 0.01; ***p < 0.001; df, degrees of freedom; P, significance level; SD, standard deviation; MDI, Mania-Depression-Interval; TEMPS-A-SF, Temperament Evaluation of Memphis, Pisa, Paris and San Diego–Auto-questionnaire, short form; CTQ-SF, Childhood Trauma Questionnaire short form