Articles
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Citation: International Journal of Bipolar Disorders 2022 10:33
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Lunar cycling in sleep and mood in individuals with bipolar disorder
Citation: International Journal of Bipolar Disorders 2022 10:32 -
Psychotic features, particularly mood incongruence, as a hallmark of severity of bipolar I disorder
The occurrence of psychotic features within mood episodes in patients with bipolar I disorder (BD I) has been associated in some studies with a more severe clinical and socio-professional profile. In contrast,...
Citation: International Journal of Bipolar Disorders 2022 10:31 -
The bipolar two-syndrome concept: questioning the shaping of a circular argument for subtyping a dimensional disorder
Citation: International Journal of Bipolar Disorders 2022 10:30 -
The course of psychiatric symptoms in older age bipolar disorder during the COVID-19 pandemic
The COVID-19 pandemic gives us the unique opportunity to study the course of psychiatric symptoms and resilience in older adults with bipolar disorder (OABD) whilst experiencing a collective long lasting stres...
Citation: International Journal of Bipolar Disorders 2022 10:29 -
Familial load of psychiatric disorders and overall functioning in patients newly diagnosed with bipolar disorder and their unaffected first-degree relatives
Overall functioning is already impaired in patients newly diagnosed with bipolar disorder (BD) and, to a lesser degree, also in their unaffected first-degree relatives (UR). Further, aggregation of psychiatric...
Citation: International Journal of Bipolar Disorders 2022 10:28 -
Correction: New vision on the mental problems of Vincent van Gogh; results from a bottom-up approach using (semi-)structured diagnostic interviews
Citation: International Journal of Bipolar Disorders 2022 10:27 -
A physically active lifestyle is associated with lower long-term incidence of bipolar disorder in a population-based, large-scale study
Physical activity has been proposed to be beneficial for the symptomatic control of bipolar disorder, but the duration of the effects, sex-specific mechanisms, and impact of exercise intensity are not known.
Citation: International Journal of Bipolar Disorders 2022 10:26 -
The interplay of daily affect and impulsivity measured by mobile surveys in bipolar disorder
Impulsivity is a prominent feature of bipolar disorder associated with various negative sequelae; moreover, it may be a precursor to shifts in affect or mood, but little is known about its association with aff...
Citation: International Journal of Bipolar Disorders 2022 10:25 -
Efficacy and safety of adjunctive therapy to lamotrigine, lithium, or valproate monotherapy in bipolar depression: a systematic review and meta-analysis of randomized controlled trials
The efficacy and safety of adjunctive therapy are unclear in bipolar depression. In this systematic review and meta-analysis, we aimed to evaluate the efficacy and safety of second-generation antipsychotic, la...
Citation: International Journal of Bipolar Disorders 2022 10:24 -
Clinical research diagnostic criteria for bipolar illness (CRDC-BP): rationale and validity
In the 1970 s, scientific research on psychiatric nosology was summarized in Research Diagnostic Criteria (RDC), based solely on empirical data, an important source for the third revision of the official nomen...
Citation: International Journal of Bipolar Disorders 2022 10:23 -
The effect of mindfulness-based cognitive therapy on rumination and a task-based measure of intrusive thoughts in patients with bipolar disorder
Preliminary evidence suggests that Mindfulness-Based Cognitive Therapy (MBCT) is a promising treatment for bipolar disorder (BD). A proposed working mechanism of MBCT in attenuating depressive symptoms is redu...
Citation: International Journal of Bipolar Disorders 2022 10:22 -
Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept
To compare characteristics of bipolar disorder patients diagnosed as DSM-5 types I (BD-1) vs. II (BD-2).
Citation: International Journal of Bipolar Disorders 2022 10:21 -
A randomised, double-blind, placebo-controlled study to evaluate the safety and efficacy of lamotrigine in the maintenance treatment of Chinese adult patients with bipolar I disorder
Lamotrigine is approved as a maintenance therapy for bipolar I disorder in many countries, including China in 2021. This study evaluated the efficacy and safety of lamotrigine in controlling relapse and/or rec...
Citation: International Journal of Bipolar Disorders 2022 10:20 -
Long-term work disability due to type I and II bipolar disorder: findings of a six-year prospective study
Bipolar disorder (BD) is one of the leading causes of disability worldwide. However, the prevalence and predictors of long-term work disability among patients with type I and II BD have scarcely been studied. ...
Citation: International Journal of Bipolar Disorders 2022 10:19 -
Psychedelics in the treatment of unipolar and bipolar depression
This is a narrative review about the role of classic and two atypical psychedelics in the treatment of unipolar and bipolar depression. Since the 1990s, psychedelics experience a renaissance in biomedical rese...
Citation: International Journal of Bipolar Disorders 2022 10:18 -
The association between variability, intensity, and persistence of suicidal ideation and prospective suicidal behavior in the systematic treatment enhancement program for bipolar disorder (STEP-BD) study
This study sought to examine the association between prospective suicidal behavior and variability, intensity, and persistence of suicidal ideation (SI) in bipolar disorder (BD).
Citation: International Journal of Bipolar Disorders 2022 10:17 -
Euthymic patients with predominantly manic polarity avoid happy faces in a dot probe task
Some studies suggest a mood-congruent attentional bias in bipolar patients. However, for euthymic patients, especially in dependence on the predominant polarity, there is little and inconsistent data. A cleare...
Citation: International Journal of Bipolar Disorders 2022 10:16 -
Using decision-analysis modelling to estimate the economic impact of the identification of unrecognised bipolar disorder in primary care: the untapped potential of screening
Patients with bipolar disorder are often unrecognised and misdiagnosed with major depressive disorder leading to higher direct costs and pressure on the medical system. Novel screening tools may mitigate the p...
Citation: International Journal of Bipolar Disorders 2022 10:15 -
Associations between circadian misalignment and telomere length in BD: an actigraphy study
Life expectancy is significantly decreased in bipolar disorder (BD). This is associated with accelerated cellular aging which can be estimated by telomere length (TL). However, specific determinants of shorter...
Citation: International Journal of Bipolar Disorders 2022 10:14 -
Is cognitive behaviour therapy applicable to individuals diagnosed with bipolar depression or suboptimal mood stabilizer treatment: a secondary analysis of a large pragmatic effectiveness trial
Efficacy trials of medications and/or psychological interventions for bipolar disorders (BD) aim to recruit homogenous samples of patients who are euthymic and such populations show high levels of adherence to...
Citation: International Journal of Bipolar Disorders 2022 10:13 -
Anticipating manic and depressive transitions in patients with bipolar disorder using early warning signals
In bipolar disorder treatment, accurate episode prediction is paramount but remains difficult. A novel idiographic approach to prediction is to monitor generic early warning signals (EWS), which may manifest i...
Citation: International Journal of Bipolar Disorders 2022 10:12 -
Environmental factors in offspring of parents with mood disorders and their role in parent–child transmission: findings from a 14-year prospective high-risk study
The factors involved in the transmission of mood disorders are only partially elucidated. Aside from genes, the family environment might play a crucial role in parent–child transmission. Our goals were to (1) ...
Citation: International Journal of Bipolar Disorders 2022 10:11 -
Evaluating the quality, safety, and functionality of commonly used smartphone apps for bipolar disorder mood and sleep self-management
Individuals with bipolar disorder (BD) are increasingly turning to smartphone applications (apps) for health information and self-management support. While reviews have raised concerns regarding the effectiven...
Citation: International Journal of Bipolar Disorders 2022 10:10 -
Omega-3 fatty acids in bipolar patients with a low omega-3 index and reduced heart rate variability: the “BIPO-3” trial
Research suggests that a low omega-3 index may contribute to the low heart rate variability and the increased risk of cardiovascular morbidity and mortality in bipolar disorders. However, so far, no interventi...
Citation: International Journal of Bipolar Disorders 2022 10:9 -
The relations between executive functions and occupational functioning in individuals with bipolar disorder: a scoping review
Patients with bipolar disorder experience impairments in their occupational functioning, despite remission of symptoms. Previous research has shown that neurocognitive deficits, especially deficits in executiv...
Citation: International Journal of Bipolar Disorders 2022 10:8 -
A pilot trial of quetiapine, lithium, or placebo added to divalproex sodium for hypomanic or manic episodes in ambulatory adults with bipolar I disorder
Many patients with bipolar I disorder do not respond to monotherapy treatment with mood-stabilizing medications, and combination regimens are commonly used in both inpatient and outpatient settings for the acu...
Citation: International Journal of Bipolar Disorders 2022 10:7 -
Sleep disturbances in the context of neurohormonal dysregulation in patients with bipolar disorder
Sleep dysfunction is a core symptom in bipolar disorder (BD), especially during major mood episodes. This study investigated the possible link between subjective and objective sleep disturbances in inter-episo...
Citation: International Journal of Bipolar Disorders 2022 10:6 -
A call for improving lithium literacy among clinicians and patients
Citation: International Journal of Bipolar Disorders 2022 10:5 -
Estimated glomerular filtration rate in Korean patients exposed to long-term lithium maintenance therapy
Lithium-induced nephrotoxicity has long been debated. However, it has been rarely explored in Asian populations. The aim of the present study was to assess the effect of lithium maintenance therapy on estimate...
Citation: International Journal of Bipolar Disorders 2022 10:4 -
Dissecting the genetic architecture of suicide attempt and repeated attempts in Korean patients with bipolar disorder using polygenic risk scores
Bipolar disorder (BD) has the greatest suicide risk among mental and physical disorders. A recent genome-wide association study (GWAS) of European ancestry (EUR) samples revealed that the genetic etiology of s...
Citation: International Journal of Bipolar Disorders 2022 10:3 -
Neuropsychological exponents for the driving ability in remitted bipolar patients
Bipolar disorder (BD) is associated with cognitive deficits regardless of the phase of the disease. Medications used in treatment are an additional factor that may affect cognitive performance. Poor cognitive ...
Citation: International Journal of Bipolar Disorders 2022 10:2 -
The big five model in bipolar disorder: a latent profile analysis and its impact on longterm illness severity
Using a personality typing approach, we investigated the relationship between personality profiles and the prediction of longterm illness severity in patients with bipolar disorder (BD). While previous researc...
Citation: International Journal of Bipolar Disorders 2022 10:1 -
A comparison of the 33-item Hypomania Checklist with the 33-item Hypomania Checklist-external assessment for the detection of bipolar disorder in adolescents
Adolescents with bipolar disorder (BD) are often misdiagnosed as having major depressive disorder (MDD), which delays appropriate treatment and leads to adverse outcomes. The aim of this study was to compare t...
Citation: International Journal of Bipolar Disorders 2021 9:41 -
Antidepressant efficacy of low-frequency repetitive transcranial magnetic stimulation in antidepressant-nonresponding bipolar depression: a single-blind randomized sham-controlled trial
To examine the antidepressant efficacy and response predictors of R-DLPFC-LF rTMS for antidepressant-nonresponding BD.
Citation: International Journal of Bipolar Disorders 2021 9:40 -
How to make online mood-monitoring in bipolar patients a success? A qualitative exploration of requirements
The Life-Chart Method (LCM) is an effective self-management treatment option in bipolar disorder (BD). There is insufficient knowledge about the consumers’ needs and desires for an e-monitoring solution. The f...
Citation: International Journal of Bipolar Disorders 2021 9:39 -
Voice analyses using smartphone-based data in patients with bipolar disorder, unaffected relatives and healthy control individuals, and during different affective states
Voice features have been suggested as objective markers of bipolar disorder (BD).
Citation: International Journal of Bipolar Disorders 2021 9:38 -
The German research consortium for the study of bipolar disorder (BipoLife): a magnetic resonance imaging study protocol
Bipolar disorder is one of the most severe mental disorders. Its chronic course is associated with high rates of morbidity and mortality, a high risk of suicide and poor social and occupational outcomes. Despi...
Citation: International Journal of Bipolar Disorders 2021 9:37 -
Mania and bipolar depression: complementing not opposing poles—a post-hoc analysis of mixed features in manic and hypomanic episodes
Depending on the classification system used, 5–40% of manic subjects present with concomitant depressive symptoms. This post-hoc analysis evaluates the hypothesis that (hypo)manic subjects have a higher burden...
Citation: International Journal of Bipolar Disorders 2021 9:36 -
The course of bipolar disorder in pregnant versus non-pregnant women
Although it has been suggested that pregnancy may influence the course of bipolar disorder (BD), studies show contradictory results. Until now, no studies included a finegrained validated method to report mood...
Citation: International Journal of Bipolar Disorders 2021 9:35 -
Characterization of affective lability across subgroups of psychosis spectrum disorders
Affective lability is elevated and associated with increased clinical burden in psychosis spectrum disorders. The extent to which the level, structure and dispersion of affective lability varies between the sp...
Citation: International Journal of Bipolar Disorders 2021 9:34 -
Affective lability as a prospective predictor of subsequent bipolar disorder diagnosis: a systematic review
The early pathogenesis and precursors of Bipolar Disorder (BD) are poorly understood. There is some cross-sectional and retrospective evidence of affective lability as a predictor of BD, but this is subject to...
Citation: International Journal of Bipolar Disorders 2021 9:33 -
Long-term outcome of postpartum psychosis: a prospective clinical cohort study in 106 women
We aimed to investigate the outcome of postpartum psychosis over a four-year follow-up, and to identify potential clinical markers of mood/psychotic episodes outside of the postpartum period.
Citation: International Journal of Bipolar Disorders 2021 9:31 -
Correction to: Using density of antecedent events and trajectory path analysis to investigate family-correlated patterns of onset of bipolar I disorder: a comparison of cohorts from Europe and USA
Citation: International Journal of Bipolar Disorders 2021 9:32 -
The futility of long-term predictions in bipolar disorder: mood fluctuations are the result of deterministic chaotic processes
Understanding the underlying architecture of mood regulation in bipolar disorder (BD) is important, as we are starting to conceptualize BD as a more complex disorder than one of recurring manic or depressive e...
Citation: International Journal of Bipolar Disorders 2021 9:30 -
Using density of antecedent events and trajectory path analysis to investigate family-correlated patterns of onset of bipolar I disorder: a comparison of cohorts from Europe and USA
Major contributors to the global burden of bipolar disorders (BD) are the early age at onset (AAO) and the co-occurrence of non-mood disorders before and after the onset of BD. Using data from two independent ...
Citation: International Journal of Bipolar Disorders 2021 9:29 -
Late chronotype predicts more depressive symptoms in bipolar disorder over a 5 year follow-up period
There is increasing evidence that bipolar disorder is influenced by circadian timing, including the timing of sleep and waking activities. Previous studies in bipolar disorder have shown that people with later...
Citation: International Journal of Bipolar Disorders 2021 9:28 -
Valproic acid autoinduction: a case-based review
Although valproic acid (VPA) induces the metabolism of multiple other drugs, the clinical reports of VPA autoinduction are rare. A comprehensive literature search yielded only one published case series, which ...
Citation: International Journal of Bipolar Disorders 2021 9:27 -
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts w...
Citation: International Journal of Bipolar Disorders 2021 9:26 -
Lurasidone in the long-term treatment of Japanese patients with bipolar I disorder: a 52 week open label study
The current study evaluated the long-term (52 week) safety and impact on symptom measures of lurasidone (with or without lithium or valproate) for the treatment of bipolar I disorder in Japanese patients.
Citation: International Journal of Bipolar Disorders 2021 9:25
- ISSN: 2194-7511 (electronic)