Articles
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Citation: International Journal of Bipolar Disorders 2017 5:21
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Awaiting accurate scientific evidence: Progression or “profiles” in bipolar disorder?
This letter is written in response to a review recently published in the journal. The aim is to highlight a potential methodological limitation common to many studies comparing bipolar patients with few previo...
Citation: International Journal of Bipolar Disorders 2017 5:14 -
Methodological considerations regarding Joyce et al. 2016
Citation: International Journal of Bipolar Disorders 2017 5:12 -
Impairment in emotion perception from body movements in individuals with bipolar I and bipolar II disorder is associated with functional capacity
Individuals with bipolar disorder present with moderate impairments in social cognition during the euthymic state. The impairment extends to theory of mind and to the perception of emotion in faces and voices,...
Citation: International Journal of Bipolar Disorders 2017 5:13 -
Cognitive impairments and predominant polarity in bipolar disorder: a cross-sectional study
Bipolar disorder (BD) patients exhibit cognitive impairments during euthymic states. Studies suggest that manic episodes may be correlated to cognitive impairments. The present study investigated the relations...
Citation: International Journal of Bipolar Disorders 2017 5:15 -
Lithium in the episode and suicide prophylaxis and in augmenting strategies in patients with unipolar depression
Depressive disorders are a leading cause of the global burden of disease and are associated with high recurrent often continuing morbidity and high excess mortality by suicide and cardiovascular disease. Whils...
Citation: International Journal of Bipolar Disorders 2017 5:11 -
Self-poisoning suicide deaths in people with bipolar disorder: characterizing a subgroup and identifying treatment patterns
To characterize self-poisoning suicide deaths in BD compared to other suicide decedents.
Citation: International Journal of Bipolar Disorders 2017 5:16 -
Cognitive remediation for bipolar patients with objective cognitive impairment: a naturalistic study
Many bipolar patients (BP) are affected by cognitive impairments and reduced psychosocial function even after complete remission. In the present naturalistic study, we developed a tailored cognitive remediatio...
Citation: International Journal of Bipolar Disorders 2017 5:8 -
Prodrome or risk syndrome: what’s in a name?
In the last decade, an increasing number of publications have examined the precursors of bipolar disorders (BD) and attempted to clarify the early origins and illness trajectory. This is a complex task as the...
Citation: International Journal of Bipolar Disorders 2017 5:7 -
Erratum to: Online information seeking by patients with bipolar disorder: results from an international multisite survey
Citation: International Journal of Bipolar Disorders 2017 5:18 -
Poor quality of life and functioning in bipolar disorder
This study explores the association of demographic and clinical features with quality of life and functioning in individuals with bipolar disorder.
Citation: International Journal of Bipolar Disorders 2017 5:10 -
Use of physical restraints among patients with bipolar disorder in Ethiopian Mental Specialized Hospital, outpatient department: cross-sectional study
Even though United Nation announced that all persons with a mental illness shall be treated with humanity and respect for the inherent dignity of the human being, up to now, the use of coercion (physical restr...
Citation: International Journal of Bipolar Disorders 2017 5:17 -
Long-term use of lurasidone in patients with bipolar disorder: safety and effectiveness over 2 years of treatment
Bipolar disorder is a chronic illness with a 2-year recurrence rate of approximately 50% among individuals receiving treatment in the community. The aim of this 18-month, open-label, continuation study was to ...
Citation: International Journal of Bipolar Disorders 2017 5:9 -
A pilot study to determine whether combinations of objectively measured activity parameters can be used to differentiate between mixed states, mania, and bipolar depression
Until recently, actigraphy studies in bipolar disorders focused on sleep rather than daytime activity in mania or depression, and have failed to analyse mixed episodes separately. Furthermore, even those studi...
Citation: International Journal of Bipolar Disorders 2017 5:5 -
Pilot study of a culturally adapted psychoeducation (CaPE) intervention for bipolar disorder in Pakistan
Despite the use of maintenance medication, recurrence rates in bipolar affective disorder (BPAD) are high. To date, there are no clinical trials that have investigated the use of psychological interventions i...
Citation: International Journal of Bipolar Disorders 2017 5:3 -
Ethical perspectives on recommending digital technology for patients with mental illness
The digital revolution in medicine not only offers exciting new directions for the treatment of mental illness, but also presents challenges to patient privacy and security. Changes in medicine are part of the...
Citation: International Journal of Bipolar Disorders 2017 5:6 -
A systematic review of the frequency and severity of manic symptoms reported in studies that compare phenomenology across children, adolescents and adults with bipolar disorders
In the last two decades, there has been a significant increase in the diagnosis of Bipolar Disorder (BD) in children. The notion of prepubertal onsets of BD is not without controversy, with researchers debatin...
Citation: International Journal of Bipolar Disorders 2017 5:4 -
American tertiary clinic-referred bipolar II disorder versus bipolar I disorder associated with hastened depressive recurrence
Bipolar disorder (BD) is a chronic, frequently comorbid condition characterized by high rates of mood episode recurrence and suicidality. Little is known about prospective longitudinal characterization of BD ...
Citation: International Journal of Bipolar Disorders 2017 5:2 -
The seroprevalence of antithyroid peroxidase antibodies in bipolar families and bipolar twins: results from two longitudinal studies
Previous studies of our group among bipolar offspring and bipolar twins showed significant higher prevalence’s and levels of antithyroid peroxidase antibodies (TPO-Abs) in offspring and co-twins (without a moo...
Citation: International Journal of Bipolar Disorders 2017 5:1 -
Lithium side effects and toxicity: prevalence and management strategies
Despite its virtually universal acceptance as the gold standard in treating bipolar disorder, prescription rates for lithium have been decreasing recently. Although this observation is multifactorial, one obvi...
Citation: International Journal of Bipolar Disorders 2016 4:27 -
Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting
Mood stabilizers like lithium and anticonvulsants are used in bipolar and related psychotic disorders. There is a lack of knowledge of the relationship of these medications and cognition in the psychosis spect...
Citation: International Journal of Bipolar Disorders 2016 4:24 -
Electronic monitoring of self-reported mood: the return of the subjective?
This narrative review describes recent developments in the use of technology for utilizing the self-monitoring of mood, provides some relevant background, and suggests some promising directions. Subjective exp...
Citation: International Journal of Bipolar Disorders 2016 4:28 -
Aims and structure of the German Research Consortium BipoLife for the study of bipolar disorder
Bipolar disorder is a severe and heterogeneous mental disorder. Despite great advances in neuroscience over the past decades, the precise causative mechanisms at the transmitter, cellular or network level have...
Citation: International Journal of Bipolar Disorders 2016 4:26 -
Bipolar disorder in the digital age: new tools for the same illness
“Nothing is more difficult than to ascertain the length of time that a maniacal patient can exist without sleep.”—Dr. Sutherland (Br J Psychiatry 7(37):1–19, 1861). Dr. Sutherland’s patient was suffering from an ...
Citation: International Journal of Bipolar Disorders 2016 4:25 -
Bipolar disorder in children and adolescents: diagnostic inpatient rates from 2000 to 2013 in Germany
Despite growing consensus on nosology and epidemiology of bipolar disorder (BD) in minors, differences remain. We contribute to this discussion by measuring long-term trends in the inpatient discharge rates of...
Citation: International Journal of Bipolar Disorders 2016 4:23 -
Psychometric properties and validation of a four-item version of the Strauss–Carpenter scale in bipolar disorder
Bipolar disorder is a chronic illness that impairs functioning and affects the quality of life of patients. The onset of this illness usually occurs at an early age, and the risk of relapse remains high for de...
Citation: International Journal of Bipolar Disorders 2016 4:22 -
Symptom profiles and illness course among Anabaptist and Non-Anabaptist adults with major mood disorders
Anabaptists comprise large and growing Amish and Mennonite populations with a unique genetic heritage and cultural background. Little is known about the symptoms and course of major mood disorders in Anabaptis...
Citation: International Journal of Bipolar Disorders 2016 4:21 -
No differences in visual theory of mind abilities between euthymic bipolar patients and healthy controls
Research on theory of mind (ToM) abilities in patients with bipolar disorder has yielded conflicting results. Meta-analyses point to a stable moderate impairment in remitted patients, but factors such as subsy...
Citation: International Journal of Bipolar Disorders 2016 4:20 -
Is treatment for bipolar disorder more effective earlier in illness course? A comprehensive literature review
We aimed to investigate a key element of the early intervention approach; whether treatment at an earlier stage of bipolar disorder is more effective than later in its course.
Citation: International Journal of Bipolar Disorders 2016 4:19 -
Mixed mania associated with cessation of breastfeeding
This case chronicles the unique presentation of psychotic mixed mania in a female 5 months after parturition and 1 week following breastfeeding discontinuation, highlighting a rarely recognized mania risk fact...
Citation: International Journal of Bipolar Disorders 2016 4:18 -
Online information seeking by patients with bipolar disorder: results from an international multisite survey
Information seeking is an important coping mechanism for dealing with chronic illness. Despite a growing number of mental health websites, there is little understanding of how patients with bipolar disorder us...
Citation: International Journal of Bipolar Disorders 2016 4:17 -
Behavioral measures and self-report of impulsivity in bipolar disorder: no association between Stroop test and Barratt Impulsiveness Scale
Impulsivity as a tendency to act quickly without considering future consequences has been proposed as a dimensional factor in bipolar disorder. It can be measured using behavioral tasks and self-report questio...
Citation: International Journal of Bipolar Disorders 2016 4:16 -
Current irritability associated with hastened depressive recurrence and delayed depressive recovery in bipolar disorder
Current irritability is associated with greater retrospective and current bipolar disorder (BD) illness severity; less is known about prospective longitudinal implications of current irritability. We examined ...
Citation: International Journal of Bipolar Disorders 2016 4:15 -
Does CRP predict outcome in bipolar disorder in regular outpatient care?
The association between inflammation and the course of mood disorders is receiving increased attention. This study aims to investigate whether a sub-group of patients with BD can be identified for which a high...
Citation: International Journal of Bipolar Disorders 2016 4:14 -
Bipolar disorder and diabetes mellitus: evidence for disease-modifying effects and treatment implications
Bipolar disorder refers to a group of chronic psychiatric disorders of mood and energy levels. While dramatic psychiatric symptoms dominate the acute phase of the diseases, the chronic course is often determin...
Citation: International Journal of Bipolar Disorders 2016 4:13 -
Repeated salivary daytime cortisol and onset of mood episodes in offspring of bipolar parents
Differences in cortisol secretion may differentiate individuals at high compared to low genetic risk for bipolar disorder (BD) and predict the onset or recurrence of mood episodes. The objectives of this study...
Citation: International Journal of Bipolar Disorders 2016 4:12 -
Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene–environment interaction study
Genetic vulnerability to environmental stressors is yet to be clarified in bipolar disorder (BD), a complex multisystem disorder in which immune dysfunction and infectious insults seem to play a major role in ...
Citation: International Journal of Bipolar Disorders 2016 4:11 -
Big data for bipolar disorder
The delivery of psychiatric care is changing with a new emphasis on integrated care, preventative measures, population health, and the biological basis of disease. Fundamental to this transformation are big da...
Citation: International Journal of Bipolar Disorders 2016 4:10 -
Biological rhythms are independently associated with quality of life in bipolar disorder
Evidence suggests that patients with bipolar disorder (BD) experience biological rhythm disturbances; however, no studies have examined the impact of this disruption on quality of life (QOL). The aim of this s...
Citation: International Journal of Bipolar Disorders 2016 4:9 -
The direct and indirect effects of lurasidone monotherapy on functional improvement among patients with bipolar depression: results from a randomized placebo-controlled trial
Bipolar depression is characterized by depressive symptoms and impairment in many areas of functioning, including work, family, and social life. The objective of this study was to assess the independent, direc...
Citation: International Journal of Bipolar Disorders 2016 4:7 -
Development and validation of the BD SX: a brief measure of mood and symptom variability for use with adults with bipolar disorder
Ecological momentary sampling in BD research requires brief symptom measures with low cognitive demands to maximize data collection across the range of BD symptomatology. We developed the BD Sx cognizant of the c...
Citation: International Journal of Bipolar Disorders 2016 4:8 -
Behavioral and emotional adverse events of drugs frequently used in the treatment of bipolar disorders: clinical and theoretical implications
Behavioral and emotional adverse events induced by drugs commonly prescribed to patients with bipolar disorders are of paramount importance to clinical practice and research. However, no reviews on the topic h...
Citation: International Journal of Bipolar Disorders 2016 4:6 -
Bipolar disorder and antithyroid antibodies: review and case series
Mood disorders and circulating thyroid antibodies are very prevalent in the population and their concomitant occurrence may be due to chance. However, thyroid antibodies have been repeatedly hypothesized to p...
Citation: International Journal of Bipolar Disorders 2016 4:5 -
Harnessing the potential of community-based participatory research approaches in bipolar disorder
Despite the rapid growth in the sophistication of research on bipolar disorder (BD), the field faces challenges in improving quality of life (QoL) and symptom outcomes, adapting treatments for marginalized com...
Citation: International Journal of Bipolar Disorders 2016 4:4 -
Circadian rhythmicity in emerging mood disorders: state or trait marker?
Circadian rhythm disturbances overlap with the symptoms of mood episodes and may trigger or prolong mood symptoms. There is limited research on the role of circadian disturbances in mood disorders in young peo...
Citation: International Journal of Bipolar Disorders 2016 4:3 -
The role of childhood trauma in bipolar disorders
This review will discuss the role of childhood trauma in bipolar disorders. Relevant studies were identified via Medline (PubMed) and PsycINFO databases published up to and including July 2015. This review con...
Citation: International Journal of Bipolar Disorders 2016 4:2 -
Lithium overdosage and related tests
Lithium acts biochemically through the inositol depletion in brain cortex. At low doses, however, it is partly effective and/or ineffective, whereas in high concentrations is toxic. We would like to make one p...
Citation: International Journal of Bipolar Disorders 2016 4:1 -
Will mania survive DSM-5 and ICD-11?
As a natural phenomenon, mania without major depression will of course survive DSM-5 and ICD-11, but following its integration as a diagnosis into bipolar-I disorder (BP-I) in those manuals, BP-I will be more ...
Citation: International Journal of Bipolar Disorders 2015 3:24 -
Treatment of lithium intoxication: facing the need for evidence
Lithium has been used as the gold standard in the treatment of major depressive and bipolar disorders for decades. Due to its narrow therapeutic index, lithium toxicity is a common clinical problem. Although r...
Citation: International Journal of Bipolar Disorders 2015 3:23 -
Low self-recognition and awareness of past hypomanic and manic episodes in the general population
Bipolar disorder is often underdiagnosed and undertreated. Its detection and correct diagnosis highly relies on the report of past hypomanic or manic episodes. We investigated the recognition and awareness of ...
Citation: International Journal of Bipolar Disorders 2015 3:22
- ISSN: 2194-7511 (electronic)