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  1. Review

    The clinical trajectory of emerging bipolar disorder among the high-risk offspring of bipolar parents: current understanding and future considerations

    Relatively little is known about the onset of bipolar disorder, yet the early illness course is already associated with significant morbidity and mortality. Therefore, characterizing the bipolar illness trajec...

    A. Duffy, C. Vandeleur, N. Heffer and M. Preisig

    International Journal of Bipolar Disorders 2017 5:37

    Published on: 22 November 2017

  2. Research

    Anxiety, irritability, and agitation as indicators of bipolar mania with depressive symptoms: a post hoc analysis of two clinical trials

    Symptoms of anxiety, irritability, and agitation (AIA) are prevalent among patients with bipolar I disorder (BD-I) mania with depressive symptoms, and could potentially be used to aid physicians in the identif...

    Trisha Suppes, Jonas Eberhard, Ole Lemming, Allan H. Young and Roger S. McIntyre

    International Journal of Bipolar Disorders 2017 5:36

    Published on: 6 November 2017

  3. Review

    Animal models for bipolar disorder: from bedside to the cage

    Bipolar disorder is characterized by recurrent manic and depressive episodes. Patients suffering from this disorder experience dramatic mood swings with a wide variety of typical behavioral facets, affecting o...

    Dominik K. E. Beyer and Nadja Freund

    International Journal of Bipolar Disorders 2017 5:35

    Published on: 13 October 2017

  4. Research

    Does perfectionism in bipolar disorder pedigrees mediate associations between anxiety/stress and mood symptoms?

    Bipolar disorder (BD) and the anxiety disorders are highly comorbid. The present study sought to examine perfectionism and goal attainment values as potential mechanisms of known associations between anxiety, ...

    Justine Corry, Melissa Green, Gloria Roberts, Janice M. Fullerton, Peter R. Schofield and Philip B. Mitchell

    International Journal of Bipolar Disorders 2017 5:34

    Published on: 6 October 2017

  5. Research

    The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder

    Although bipolar disorder (BD) and borderline personality disorder (BPD) share clinical characteristics and frequently co-occur, their interrelationship is controversial. Especially, the differentiation of rap...

    Georg Riemann, Nadine Weisscher, Robert M. Post, Lori Altshuler, Susan McElroy, Marc A. Frye, Paul E. Keck Jr., Gabriele S. Leverich, Trisha Suppes, Heinz Grunze, Willem A. Nolen and Ralph W. Kupka

    International Journal of Bipolar Disorders 2017 5:31

    Published on: 25 September 2017

  6. Erratum

    Erratum to: Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study

    In the original version of this article (Wu et al. 2017), published on 1 September 2017, the name of author ‘Bo Cao’ was wrongly displayed. In this Erratum the incorrect name and correct name are shown. The origi...

    Mon-Ju Wu, Benson Mwangi, Ives Cavalcante Passos, Isabelle E. Bauer, Bo Cao, Thomas W. Frazier, Giovana B. Zunta-Soares and Jair C. Soares

    International Journal of Bipolar Disorders 2017 5:33

    Published on: 18 September 2017

    The original article was published in International Journal of Bipolar Disorders 2017 5:32

  7. Research

    Childhood maltreatment and the medical morbidity in bipolar disorder: a case–control study

    Childhood maltreatment (abuse and neglect) can have long-term deleterious consequences, including increased risk for medical and psychiatric illnesses, such as bipolar disorder in adulthood. Emerging evidence ...

    Georgina M. Hosang, Helen L. Fisher, Rudolf Uher, Sarah Cohen-Woods, Barbara Maughan, Peter McGuffin and Anne E. Farmer

    International Journal of Bipolar Disorders 2017 5:30

    Published on: 7 September 2017

  8. Research

    Prediction of vulnerability to bipolar disorder using multivariate neurocognitive patterns: a pilot study

    Bipolar disorder (BD) is a common disorder with high reoccurrence rate in general population. It is critical to have objective biomarkers to identify BD patients at an individual level. Neurocognitive signatur...

    Mon-Ju Wu, Benson Mwangi, Ives Cavalcante Passos, Isabelle E. Bauer, Bo Cao, Thomas W. Frazier, Giovana B. Zunta-Soares and Jair C. Soares

    International Journal of Bipolar Disorders 2017 5:32

    Published on: 1 September 2017

    The Erratum to this article has been published in International Journal of Bipolar Disorders 2017 5:33

  9. Research

    Clinical correlates of age at onset distribution in bipolar disorder: a comparison between diagnostic subgroups

    Admixture analysis of age at onset (AAO) has helped delineating the clinical profile of early onset (EO) bipolar disorder (BD). However, there is scarce evidence comparing the distributional properties of AAO ...

    Mirko Manchia, Giuseppe Maina, Bernardo Carpiniello, Federica Pinna, Luca Steardo, Virginia D’Ambrosio, Virginio Salvi, Martin Alda, Alfonso Tortorella and Umberto Albert

    International Journal of Bipolar Disorders 2017 5:28

    Published on: 21 August 2017

  10. Research

    Lifetime eating disorder comorbidity associated with delayed depressive recovery in bipolar disorder

    Although eating disorders (EDs) are common in bipolar disorder (BD), little is known regarding their longitudinal consequences. We assessed prevalence, clinical correlates, and longitudinal depressive severity...

    Danielle R. Balzafiore, Natalie L. Rasgon, Laura D. Yuen, Saloni Shah, Hyun Kim, Kathryn C. Goffin, Shefali Miller, Po W. Wang and Terence A. Ketter

    International Journal of Bipolar Disorders 2017 5:25

    Published on: 12 August 2017

  11. Review

    Online ethics: where will the interface of mental health and the internet lead us?

    While e-health initiatives are poised to revolutionize delivery and access to mental health care, conducting clinical research online involves specific contextual and ethical considerations. Face-to-face psych...

    Victoria Cosgrove, Emma Gliddon, Lesley Berk, David Grimm, Sue Lauder, Seetal Dodd, Michael Berk and Trisha Suppes

    International Journal of Bipolar Disorders 2017 5:26

    Published on: 6 August 2017

  12. Research

    Long-term lithium treatment in bipolar disorder: effects on glomerular filtration rate and other metabolic parameters

    Concerns about potential adverse effects of long-term exposure to lithium as a mood-stabilizing treatment notably include altered renal function. However, the incidence of severe renal dysfunction; rate of dec...

    Leonardo Tondo, Maria Abramowicz, Martin Alda, Michael Bauer, Alberto Bocchetta, Lorenza Bolzani, Cynthia V. Calkin, Caterina Chillotti, Diego Hidalgo-Mazzei, Mirko Manchia, Bruno Müller-Oerlinghausen, Andrea Murru, Giulio Perugi, Marco Pinna, Giuseppe Quaranta, Daniela Reginaldi…

    International Journal of Bipolar Disorders 2017 5:27

    Published on: 1 August 2017

  13. Research

    Long-term response to mood stabilizer treatment and its clinical correlates in patients with bipolar disorders: a retrospective observational study

    The efficacy and utility of long-term prophylactic treatment in patients with bipolar disorders (BDs) have not been fully explored. This study aims to estimate the long-term clinical response of patients with ...

    Sung Woo Ahn, Ji Hyun Baek, So-Yung Yang, Yongkang Kim, Youngah Cho, Yujin Choi, Kounseok Lee, Taesung Park and Kyung Sue Hong

    International Journal of Bipolar Disorders 2017 5:24

    Published on: 9 July 2017

  14. Short communication

    Efficacy and tolerability of lithium in treating acute mania in youth with bipolar disorder: protocol for a systematic review

    Epidemiological, clinical, and high-risk studies have provided evidence that the peak period for onset of diagnosable episodes of mania and hypomania starts in mid-to-late adolescence. Moreover, clinically sig...

    A. Duffy, S. Patten, S. Goodday, A. Weir, N. Heffer and A. Cipriani

    International Journal of Bipolar Disorders 2017 5:22

    Published on: 13 June 2017

  15. Research

    Sexual distress and quality of life among women with bipolar disorder

    Information on the association between bipolar disorder (BD), sexual satisfaction, sexual function, sexual distress and quality of life (QoL) is sparse. This study aims, in women with BD, to (i) investigate se...

    Thea Sørensen, A. Giraldi and M. Vinberg

    International Journal of Bipolar Disorders 2017 5:29

    Published on: 6 June 2017

  16. Research

    1H-NMR, 1H-NMR T2-edited, and 2D-NMR in bipolar disorder metabolic profiling

    The objective of this study was to identify molecular alterations in the human blood serum related to bipolar disorder, using nuclear magnetic resonance (NMR) spectroscopy and chemometrics.

    Sumit Sethi, Mariana Pedrini, Lucas B. Rizzo, Maiara Zeni-Graiff, Caroline Dal Mas, Ana Cláudia Cassinelli, Mariane N. Noto, Elson Asevedo, Quirino Cordeiro, João G. M. Pontes, Antonio J. M. Brasil, Acioly Lacerda, Mirian A. F. Hayashi, Ronei Poppi, Ljubica Tasic and Elisa Brietzke

    International Journal of Bipolar Disorders 2017 5:23

    Published on: 4 June 2017

  17. Research

    An observational study of 110 elderly lithium-treated patients followed up for 6 years with particular reference to renal function

    Recent observational studies have focused on lithium treatment in the elderly, with particular reference to safety in terms of thyroid and renal functions. The purpose of this study was to compare the clinical...

    Alberto Bocchetta, Francesca Cabras, Martina Pinna, Antonio Poddighe, Claudia Sardu, Raffaella Ardau, Caterina Chillotti and Maria Del Zompo

    International Journal of Bipolar Disorders 2017 5:19

    Published on: 4 June 2017

  18. Research

    Impairment in emotion perception from body movements in individuals with bipolar I and bipolar II disorder is associated with functional capacity

    Individuals with bipolar disorder present with moderate impairments in social cognition during the euthymic state. The impairment extends to theory of mind and to the perception of emotion in faces and voices,...

    Anja Vaskinn, Trine Vik Lagerberg, Thomas D. Bjella, Carmen Simonsen, Ole A. Andreassen, Torill Ueland and Kjetil Sundet

    International Journal of Bipolar Disorders 2017 5:13

    Published on: 17 May 2017

  19. Research

    Cognitive impairments and predominant polarity in bipolar disorder: a cross-sectional study

    Bipolar disorder (BD) patients exhibit cognitive impairments during euthymic states. Studies suggest that manic episodes may be correlated to cognitive impairments. The present study investigated the relations...

    Gabriel Okawa Belizario, Alexandre Duarte Gigante, Cristiana Castanho de Almeida Rocca and Beny Lafer

    International Journal of Bipolar Disorders 2017 5:15

    Published on: 12 May 2017

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