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  1. The Stanley Foundation Bipolar Treatment Outcome Network (SFBN) recruited more than 900 outpatients from 1995 to 2002 from 4 sites in the United States (US) and 3 in the Netherlands and Germany (abbreviated as...

    Authors: Robert M. Post, Lori L. Altshuler, Ralph Kupka, Susan L. McElroy, Mark A. Frye, Heinz Grunze, Trisha Suppes, Paul E. Keck Jr and Willem A. Nolen

    Citation: International Journal of Bipolar Disorders 2021 9:13

    Content type: Review

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  2. Impaired working memory is a core cognitive deficit in both bipolar disorder and schizophrenia. Its study might yield crucial insights into the underpinnings of both disorders on the cognitive and neurophysiol...

    Authors: Catherine V. Barnes-Scheufler, Caroline Passow, Lara Rösler, Jutta S. Mayer, Viola Oertel, Sarah Kittel-Schneider, Silke Matura, Andreas Reif and Robert A. Bittner

    Citation: International Journal of Bipolar Disorders 2021 9:12

    Content type: Research

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  3. Internet of Things (IoT) devices for remote monitoring, diagnosis, and treatment are widely viewed as an important future direction for medicine, including for bipolar disorder and other mental illness. The nu...

    Authors: Scott Monteith, Tasha Glenn, John Geddes, Emanuel Severus, Peter C. Whybrow and Michael Bauer

    Citation: International Journal of Bipolar Disorders 2021 9:11

    Content type: Review

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  4. Lithium is considered the gold standard treatment for bipolar disorder (BD). Current clinical guidelines and scientific evidence support its use as a first-line treatment in BD. However, over the last two deca...

    Authors: Xabier Pérez de Mendiola, Diego Hidalgo-Mazzei, Eduard Vieta and Ana González-Pinto

    Citation: International Journal of Bipolar Disorders 2021 9:10

    Content type: Research

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  5. Prefrontal dopamine D1 receptor (D1R) mediates behavior related to anxiety, reward and memory, and is involved in inflammatory processes, all of which are affected in bipolar disorder. Interleukin-6 (IL-6), a ...

    Authors: Dominik K. E. Beyer, Annika Mattukat and Nadja Freund

    Citation: International Journal of Bipolar Disorders 2021 9:9

    Content type: Research

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  6. The Cortisol Awakening Response (CAR) measured as the transient increase in cortisol levels following morning awakening appears to be a distinct feature of the HPA axis. Patients with bipolar disorder (BD) exp...

    Authors: Maria Faurholt-Jepsen, Vibe Gedsø Frøkjær, Arafat Nasser, Niklas Rye Jørgensen, Lars Vedel Kessing and Maj Vinberg

    Citation: International Journal of Bipolar Disorders 2021 9:8

    Content type: Research

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  7. Visible light, predominantly in the blue range, affects mood and circadian rhythm partly by activation of the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). The light-induc...

    Authors: Helle Østergaard Madsen, Shakoor Ba-Ali, Steffen Heegaard, Ida Hageman, Ulla Knorr, Henrik Lund-Andersen, Klaus Martiny and Lars Vedel Kessing

    Citation: International Journal of Bipolar Disorders 2021 9:7

    Content type: Research

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  8. Bipolar disorder is a severe psychiatric illness with poor prognosis and problematic and suboptimal treatments. Understanding the pathoetiologic mechanisms may improve treatment and outcomes.

    Authors: Rif S. El-Mallakh, Yonglin Gao and Pan You

    Citation: International Journal of Bipolar Disorders 2021 9:6

    Content type: Review

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  9. Bipolar disorder (BD) is associated with excess and premature cardiovascular mortality. Elevated blood pressure (BP) is a leading contributor to cardiovascular risk. However, few studies have examined BP in BD...

    Authors: Niall M. McGowan, Molly Nichols, Amy C. Bilderbeck, Guy M. Goodwin and Kate E. A. Saunders

    Citation: International Journal of Bipolar Disorders 2021 9:5

    Content type: Research

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  10. In vitro studies have demonstrated that lithium has antiviral properties, but evidence from human studies is scarce. Lithium is used as a mood stabilizer to treat patients with bipolar disorder. Here, the aim ...

    Authors: Mikael Landén, Henrik Larsson, Paul Lichtenstein, Johan Westin and Jie Song

    Citation: International Journal of Bipolar Disorders 2021 9:4

    Content type: Research

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  11. Bipolar Disorders (BD) are disabling and severe psychiatric disorders, commonly perceived as equally affecting both men and women. The prevalence of BD in the general population has been growing over the last ...

    Authors: Bernardo Dell’Osso, Rita Cafaro and Terence A. Ketter

    Citation: International Journal of Bipolar Disorders 2021 9:3

    Content type: Short Communication

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  12. Both bipolar disorder and major depressive disorder are characterized by difficulties in emotion regulation. Little is known about which specific emotion regulatory patterns may be transdiagnostic versus disor...

    Authors: Christie W. Musket, Natasha S. Hansen, Keith M. Welker, Kirsten E. Gilbert and June Gruber

    Citation: International Journal of Bipolar Disorders 2021 9:2

    Content type: Research

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  13. Lithium-induced nephropathy is a known long-term complication, sometimes limiting the use of lithium as mood stabilizer. The aim of this study is to establish the incidence of chronic kidney disease and the ra...

    Authors: Arjan M. Van Alphen, Tessa M. Bosch, Ralph W. Kupka and Rocco Hoekstra

    Citation: International Journal of Bipolar Disorders 2021 9:1

    Content type: Research

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  14. To identify possible socio-demographic and clinical factors associated with Good Outcome (GO) as compared with Poor Outcome (PO) in adult patients diagnosed with Bipolar Disorder (BD) who received long-term tr...

    Authors: Diane Grillault Laroche, Bruno Etain, Emanuel Severus, Jan Scott and Frank Bellivier

    Citation: International Journal of Bipolar Disorders 2020 8:40

    Content type: Review

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  15. Although a growing body of literature highlights the potential benefit of smartphone-based mobile apps to aid in self-management and treatment of bipolar disorder, it is unclear whether such evidence-based app...

    Authors: Sarah Lagan, Abinaya Ramakrishnan, Evan Lamont, Aparna Ramakrishnan, Mark Frye and John Torous

    Citation: International Journal of Bipolar Disorders 2020 8:39

    Content type: Research

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  16. Self-monitoring has been shown to improve the self-management and treatment of patients with bipolar disorder. However, current self-monitoring methods are limited to once-daily retrospectively assessed mood, ...

    Authors: Fionneke M. Bos, Evelien Snippe, Richard Bruggeman, Bennard Doornbos, Marieke Wichers and Lian van der Krieke

    Citation: International Journal of Bipolar Disorders 2020 8:38

    Content type: Research

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  17. Evidence mapping is a structured approach used to synthesize the state-of-the-art in an emerging field of research when systematic reviews or meta-analyses are deemed inappropriate. We employed this strategy t...

    Authors: Jan Scott, Francesc Colom, Allan Young, Frank Bellivier and Bruno Etain

    Citation: International Journal of Bipolar Disorders 2020 8:37

    Content type: Review

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  18. When evaluating the long-term treatment response to mood stabilizers using the Alda scale, mood stabilizer combination therapy is typically considered a confounding factor, and patients receiving combination t...

    Authors: Jinyoung Lee, Ji Hyun Baek, Dongbin Lee, Sung Woo Ahn, So-Yung Yang, Yujin Choi, Yong Chun Bahk and Kyung Sue Hong

    Citation: International Journal of Bipolar Disorders 2020 8:36

    Content type: Research

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  19. The concept of misperception of sleep refers to the estimated discrepancy between subjective and objective measures of sleep. This has been assessed only in a few prior studies in individuals with Bipolar Diso...

    Authors: Henrik Myhre Ihler, Manon Meyrel, Vincent Hennion, Julia Maruani, Gregory Gross, Pierre A. Geoffroy, Trine Vik Lagerberg, Ingrid Melle, Frank Bellivier, Jan Scott and Bruno Etain

    Citation: International Journal of Bipolar Disorders 2020 8:34

    Content type: Research

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  20. Digital phenotyping promises to unobtrusively obtaining a continuous and objective input of symptomatology from patients’ daily lives. The prime example are bipolar disorders, as smartphone parameters directly...

    Authors: Ulrich W. Ebner-Priemer, Esther Mühlbauer, Andreas B. Neubauer, Holger Hill, Fabrice Beier, Philip S. Santangelo, Philipp Ritter, Nikolaus Kleindienst, Michael Bauer, Florian Schmiedek and Emanuel Severus

    Citation: International Journal of Bipolar Disorders 2020 8:35

    Content type: Research

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  21. Mindfulness- Based Cognitive Therapy (MBCT) could be a promising psychosocial intervention for people with bipolar disorder (BD). However, little is known about the feasibility of MBCT for people with BD. In t...

    Authors: Imke Hanssen, Nicole van der Horst, Marieke Boele, Marc Lochmann van Bennekom, Eline Regeer and Anne Speckens

    Citation: International Journal of Bipolar Disorders 2020 8:33

    Content type: Research

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  22. In DSM-5 activity is a core criterion for diagnosing hypomania and mania. However, there are no guidelines for quantifying changes in activity. The objectives of the study were (1) to investigate daily smartph...

    Authors: Sharleny Stanislaus, Maj Vinberg, Sigurd Melbye, Mads Frost, Jonas Busk, Jakob E. Bardram, Lars Vedel Kessing and Maria Faurholt-Jepsen

    Citation: International Journal of Bipolar Disorders 2020 8:32

    Content type: Research

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  23. On July 29, 1890 at the age of 37 years, the Dutch painter Vincent van Gogh died from the consequences of a suicide attempt with a gun 2 days earlier. Since then many medical and psychological theories were su...

    Authors: Willem A. Nolen, Erwin van Meekeren, Piet Voskuil and Willem van Tilburg

    Citation: International Journal of Bipolar Disorders 2020 8:30

    Content type: Case Report

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  24. Cognitive impairments in patients with bipolar disorder (BD) have been associated with reduced functioning. Aims: To investigate the association between (1) patient-evaluated cognitive function measured daily ...

    Authors: Maria Faurholt-Jepsen, Kamilla Woznica Miskowiak, Mads Frost, Ellen Margrethe Christensen, Helga Þórarinsdóttir, Jakob Eyvind Bardram, Maj Vinberg and Lars Vedel Kessing

    Citation: International Journal of Bipolar Disorders 2020 8:31

    Content type: Research

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  25. Psychiatrists were surveyed to obtain an overview of how they currently use technology in clinical practice, with a focus on psychiatrists who treat patients with bipolar disorder.

    Authors: Rita Bauer, Tasha Glenn, Scott Monteith, Peter C. Whybrow and Michael Bauer

    Citation: International Journal of Bipolar Disorders 2020 8:29

    Content type: Research

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  26. Many frequently used instruments fail to assess psychosocial functioning in patients with bipolar disorder. The Functioning Assessment Short Test (FAST) was developed in order to tackle this problem and to ass...

    Authors: Melis Orhan, Nicole Korten, Ralph Kupka, Patricia van Oppen, Max Stek, Eduard Vieta, Sigfried Schouws, Wouter van Ballegooijen and Annemiek Dols

    Citation: International Journal of Bipolar Disorders 2020 8:28

    Content type: Research

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  27. Psychoeducation (PE) for bipolar disorder (BD) has a first-line recommendation for the maintenance treatment phase of BD. Formats vary greatly in the number of sessions, whether offered individually or in a gr...

    Authors: Susan Zyto, Nienke Jabben, Peter F. J. Schulte, Eline J. Regeer, Peter J. J. Goossens and Ralph W. Kupka

    Citation: International Journal of Bipolar Disorders 2020 8:26

    Content type: Research

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  28. Bipolar offspring are considered a high-risk group for developing mental disorders. Developmental outcomes result from additive and interactive effects of biological vulnerability and environmental influences....

    Authors: Teija M. S. Anke, Kari Slinning, Vibeke Moe, Cathrine Brunborg, Torill S. Siqveland and Dag Vegard Skjelstad

    Citation: International Journal of Bipolar Disorders 2020 8:27

    Content type: Research

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  29. This first mixed-methods UK trial examined the feasibility and acceptability of a future definitive randomised controlled trial (RCT) to evaluate whether Family Focussed Treatment for Adolescents with Bipolar ...

    Authors: A. Sharma, M. Glod, T. Forster, R. McGovern, K. McGurk, E. Barron Millar, T. D. Meyer, D. Miklowitz, V. Ryan, L. Vale and A. Le Couteur

    Citation: International Journal of Bipolar Disorders 2020 8:24

    Content type: Research

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  30. Treatment in bipolar disorder (BD) is commonly applied as a multimodal therapy based on decision algorithms that lack an integrative understanding of molecular mechanisms or a biomarker associated clinical out...

    Authors: Alfredo B. Cuéllar-Barboza, Susan L. McElroy, Marin Veldic, Balwinder Singh, Simon Kung, Francisco Romo-Nava, Nicolas A. Nunez, Alejandra Cabello-Arreola, Brandon J. Coombes, Miguel Prieto, Hannah K. Betcher, Katherine M. Moore, Stacey J. Winham, Joanna M. Biernacka and Mark A. Frye

    Citation: International Journal of Bipolar Disorders 2020 8:23

    Content type: Review

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  31. Bipolar disorders (BD) belong to the most severe mental disorders, characterized by an early onset and recurrent, severe episodes or a chronic course with poor psychosocial functioning in a proportion of patie...

    Authors: Andrea Pfennig, Karolina Leopold, Julia Martini, Anne Boehme, Martin Lambert, Thomas Stamm, Felix Bermpohl, Andreas Reif, Sarah Kittel-Schneider, Georg Juckel, Andreas J. Fallgatter, Tilo Kircher, Andreas Jansen, Steffi Pfeiffer, Christina Berndt, Maren Rottmann-Wolf…

    Citation: International Journal of Bipolar Disorders 2020 8:22

    Content type: Study Protocols

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  32. Light therapy has been used to treat winter depression in bipolar disorder, although the dose, duration, and timing of treatment have differed. The present study is an open trial of light therapy for depressiv...

    Authors: Lotte J. E. van Hout, Lisette E. P. Rops and Claudia J. P. Simons

    Citation: International Journal of Bipolar Disorders 2020 8:17

    Content type: Short Communication

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  33. Sleep disturbances are a central feature in bipolar disorder (BD) that often persist in remission and seem to be present also in unaffected first-degree relatives (UR) of patients with BD, presenting a possibl...

    Authors: Nikolaj Folke la Cour Karottki, Klara Coello, Sharleny Stanislaus, Sigurd Melbye, Hanne Lie Kjærstad, Kimie Stefanie Ormstrup Sletved, Lars Vedel Kessing and Maj Vinberg

    Citation: International Journal of Bipolar Disorders 2020 8:16

    Content type: Research

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  34. Since its introduction in modern medicine, naturalistic observations emerged about possible uses of lithium treatment for conditions different from recurring affective disorders, for which it is still a first-...

    Authors: Andrea Murru, Mirko Manchia, Tomas Hajek, René E. Nielsen, Janusz K. Rybakowski, Gabriele Sani, Thomas G. Schulze, Leonardo Tondo and Michael Bauer

    Citation: International Journal of Bipolar Disorders 2020 8:21

    Content type: Review

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  35. Diagnostic stability of bipolar disorder (BD) in children and adolescents, beyond the first contact has been investigated sparsely. The aim of this study was to investigate the diagnostic stability of BD in ch...

    Authors: Mathilde Frahm Laursen, Rasmus W. Licht, Christoph U. Correll, Tobias Kallehauge, Ann-Eva Christensen, Maria Rodrigo-Domingo and René Ernst Nielsen

    Citation: International Journal of Bipolar Disorders 2020 8:14

    Content type: Research

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  36. To compare illness characteristics, treatment history, response and durability, and suicidality scores over a 5-year period in patients with treatment-resistant bipolar depression participating in a prospectiv...

    Authors: R. Hamish McAllister-Williams, Soraia Sousa, Arun Kumar, Teresa Greco, Mark T. Bunker, Scott T. Aaronson, Charles R. Conway and A. John Rush

    Citation: International Journal of Bipolar Disorders 2020 8:13

    Content type: Research

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  37. It can be argued that the controversy over paediatric bipolar disorder has been useful in highlighting the issue of bipolar disorder in youths generally. Arising out of this controversy is the recognition that...

    Authors: Anthony James

    Citation: International Journal of Bipolar Disorders 2020 8:19

    Content type: Letter to the Editor

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  38. Differentiating between unipolar and bipolar depression can be clinically challenging, especially at first presentation. Patterns of cortisol secretion could aid diagnostic discrimination in affective disorder...

    Authors: Andrés Herane-Vives, Danilo Arnone, Valeria de Angel, Andrew Papadopoulos, Toby Wise, Luis Alameda, Kia-Chong Chua, Allan H. Young and Anthony J. Cleare

    Citation: International Journal of Bipolar Disorders 2020 8:15

    Content type: Research

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  39. The aim of this study is to determine whether adding combination of agents with anti-inflammatory and neurotrophic effects is more efficacious than mood stabilizer alone in improving clinical symptoms, plasma ...

    Authors: Sheng-Yu Lee, Tzu-Yun Wang, Shiou-Lan Chen, Yun-Hsuan Chang, Po-See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Liang-Jen Wang, I-Hui Lee, Kao-Ching Chen, Yen-Kuang Yang, Jau-Shyong Hong and Ru-Band Lu

    Citation: International Journal of Bipolar Disorders 2020 8:11

    Content type: Research

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  40. Child maltreatment has been shown to be associated with a wide range of mental disorders, including bipolar disorders. In this 2-year follow-up study, recollections of emotional, physical and sexual abuse were...

    Authors: Ida S. Haussleiter, Eva Neumann, Sandra Lorek, Bianca Ueberberg and Georg Juckel

    Citation: International Journal of Bipolar Disorders 2020 8:10

    Content type: Research

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  41. Bipolar disorder is associated with significant functional deficits including occupational functioning. Despite the high rates of unemployment and sick leave in the patient population, only a limited number of...

    Authors: Julia Drakopoulos, Timea Sparding, Caitlin Clements, Erik Pålsson and Mikael Landén

    Citation: International Journal of Bipolar Disorders 2020 8:7

    Content type: Research

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  42. Stressful life events influence the course of affective disorders, however, the mechanisms by which they bring about phenotypic change are not entirely known.

    Authors: Ashley L. Comes, Darina Czamara, Kristina Adorjan, Heike Anderson-Schmidt, Till F. M. Andlauer, Monika Budde, Katrin Gade, Maria Hake, Janos L. Kalman, Sergi Papiol, Daniela Reich-Erkelenz, Farah Klöhn-Saghatolislam, Sabrina K. Schaupp, Eva C. Schulte, Fanny Senner, Georg Juckel…

    Citation: International Journal of Bipolar Disorders 2020 8:9

    Content type: Research

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  43. Individuals with bipolar disorder (BD) often possess maladaptive traits and present with various difficulties in psychosocial functioning. However, little is known about the intimate partners of adults with bi...

    Authors: Lisa Serravalle, Vanessa Iacono, Sheilagh Hodgins and Mark A. Ellenbogen

    Citation: International Journal of Bipolar Disorders 2020 8:8

    Content type: Research

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  44. Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown.

    Authors: Xin Qi, Yan Wen, Ping Li, Chujun Liang, Bolun Cheng, Mei Ma, Shiqiang Cheng, Lu Zhang, Li Liu, Om Prakash Kafle and Feng Zhang

    Citation: International Journal of Bipolar Disorders 2020 8:6

    Content type: Research

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  45. The issue of categorical vs. dimensional classification of bipolar disorder continues to generate controversy as it has for generations. Despite the evidence that no psychiatric disorder has discrete boundarie...

    Authors: Michael Gitlin and Gin S. Malhi

    Citation: International Journal of Bipolar Disorders 2020 8:5

    Content type: Review

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