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International Journal of Bipolar Disorders
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Articles

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  1. Efficacy trials of medications and/or psychological interventions for bipolar disorders (BD) aim to recruit homogenous samples of patients who are euthymic and such populations show high levels of adherence to...

    Authors: Jan Scott, Richard Bentall, Peter Kinderman and Richard Morriss
    Citation: International Journal of Bipolar Disorders 2022 10:13
    Content type: Research Published on:

  2. In bipolar disorder treatment, accurate episode prediction is paramount but remains difficult. A novel idiographic approach to prediction is to monitor generic early warning signals (EWS), which may manifest i...

    Authors: Fionneke M. Bos, Marieke J. Schreuder, Sandip V. George, Bennard Doornbos, Richard Bruggeman, Lian van der Krieke, Bartholomeus C. M. Haarman, Marieke Wichers and Evelien Snippe
    Citation: International Journal of Bipolar Disorders 2022 10:12
    Content type: Research Published on:

  3. The factors involved in the transmission of mood disorders are only partially elucidated. Aside from genes, the family environment might play a crucial role in parent–child transmission. Our goals were to (1) ...

    Authors: Flore Moulin, Mehdi Gholam, Marie-Pierre F. Strippoli, Enrique Castelao, Kathleen R. Merikangas, Emma K. Stapp, Pierre Marquet, Jean-Michel Aubry, Kerstin J. Plessen, Francesca Di Giacomo, Jennifer Glaus, Giorgio Pistis, Benjamin Lavigne, Julien Elowe, Setareh Ranjbar, Martin Preisig…
    Citation: International Journal of Bipolar Disorders 2022 10:11
    Content type: Research Published on:

  4. Individuals with bipolar disorder (BD) are increasingly turning to smartphone applications (apps) for health information and self-management support. While reviews have raised concerns regarding the effectiven...

    Authors: Emma Morton, Jennifer Nicholas, Linda Yang, Laura Lapadat, Steven J. Barnes, Martin D. Provencher, Colin Depp, Michelle Chan, Rhea Kulur and Erin E. Michalak
    Citation: International Journal of Bipolar Disorders 2022 10:10
    Content type: Research Published on:

  5. Research suggests that a low omega-3 index may contribute to the low heart rate variability and the increased risk of cardiovascular morbidity and mortality in bipolar disorders. However, so far, no interventi...

    Authors: Michael Berger, Florian Seemüller, Alessandra Voggt, Michael Obermeier, Franca Kirchberg, Anja Löw, Michael Riedel, Clemens von Schacky and Emanuel Severus
    Citation: International Journal of Bipolar Disorders 2022 10:9
    Content type: Research Published on:

  6. Patients with bipolar disorder experience impairments in their occupational functioning, despite remission of symptoms. Previous research has shown that neurocognitive deficits, especially deficits in executiv...

    Authors: Juul Koene, Susan Zyto, Jaap van der Stel, Natasja van Lang, Marion Ammeraal, Ralph W. Kupka and Jaap van Weeghel
    Citation: International Journal of Bipolar Disorders 2022 10:8
    Content type: Review Published on:

  7. Many patients with bipolar I disorder do not respond to monotherapy treatment with mood-stabilizing medications, and combination regimens are commonly used in both inpatient and outpatient settings for the acu...

    Authors: Victoria E. Cosgrove, Santiago Allende, Iola Gwizdowski, E. Grace Fischer, Michael Ostacher and Trisha Suppes
    Citation: International Journal of Bipolar Disorders 2022 10:7
    Content type: Research Published on:

  8. Sleep dysfunction is a core symptom in bipolar disorder (BD), especially during major mood episodes. This study investigated the possible link between subjective and objective sleep disturbances in inter-episo...

    Authors: Tom Roloff, Ida Haussleiter, Klara Meister and Georg Juckel
    Citation: International Journal of Bipolar Disorders 2022 10:6
    Content type: Research Published on:

  10. Lithium-induced nephrotoxicity has long been debated. However, it has been rarely explored in Asian populations. The aim of the present study was to assess the effect of lithium maintenance therapy on estimate...

    Authors: Yunji Cho, Dongbin Lee, Ji Hyun Baek and Kyung Sue Hong
    Citation: International Journal of Bipolar Disorders 2022 10:4
    Content type: Research Published on:

  11. Bipolar disorder (BD) has the greatest suicide risk among mental and physical disorders. A recent genome-wide association study (GWAS) of European ancestry (EUR) samples revealed that the genetic etiology of s...

    Authors: Dongbin Lee, Ji Hyun Baek, Kyooseob Ha, Eun-Young Cho, Yujin Choi, So-Yung Yang, Ji Sun Kim, Yunji Cho, Hong-Hee Won and Kyung Sue Hong
    Citation: International Journal of Bipolar Disorders 2022 10:3
    Content type: Research Published on:

  13. Using a personality typing approach, we investigated the relationship between personality profiles and the prediction of longterm illness severity in patients with bipolar disorder (BD). While previous researc...

    Authors: Niklas Ortelbach, Jonas Rote, Alice Mai Ly Dingelstadt, Anna Stolzenburg, Cornelia Koenig, Grace O’Malley, Esther Quinlivan, Jana Fiebig, Steffi Pfeiffer, Barbara König, Christian Simhandl, Michael Bauer, Andrea Pfennig and Thomas J. Stamm
    Citation: International Journal of Bipolar Disorders 2022 10:1
    Content type: Research Published on:

  14. Adolescents with bipolar disorder (BD) are often misdiagnosed as having major depressive disorder (MDD), which delays appropriate treatment and leads to adverse outcomes. The aim of this study was to compare t...

    Authors: Xu Chen, Wei Bai, Na Zhao, Sha Sha, Teris Cheung, Gabor S. Ungvari, Yuan Feng, Yu-Tao Xiang and Jules Angst
    Citation: International Journal of Bipolar Disorders 2021 9:41
    Content type: Short Communication Published on:

  15. To examine the antidepressant efficacy and response predictors of R-DLPFC-LF rTMS for antidepressant-nonresponding BD.

    Authors: Arthur D. P. Mak, Sebastiaan F. W. Neggers, Owen N. W. Leung, Winnie C. W. Chu, Jenny Y. M. Ho, Idy W. Y. Chou, Sandra S. M. Chan, Linda C. W. Lam and Sing Lee
    Citation: International Journal of Bipolar Disorders 2021 9:40
    Content type: Research Published on:

  16. The Life-Chart Method (LCM) is an effective self-management treatment option in bipolar disorder (BD). There is insufficient knowledge about the consumers’ needs and desires for an e-monitoring solution. The f...

    Authors: B. Geerling, S. M. Kelders, R. W. Kupka, A. W. M. M. Stevens and E. T. Bohlmeijer
    Citation: International Journal of Bipolar Disorders 2021 9:39
    Content type: Research Published on:

  17. Voice features have been suggested as objective markers of bipolar disorder (BD).

    Authors: Maria Faurholt-Jepsen, Darius Adam Rohani, Jonas Busk, Maj Vinberg, Jakob Eyvind Bardram and Lars Vedel Kessing
    Citation: International Journal of Bipolar Disorders 2021 9:38
    Content type: Research Published on:

  18. Bipolar disorder is one of the most severe mental disorders. Its chronic course is associated with high rates of morbidity and mortality, a high risk of suicide and poor social and occupational outcomes. Despi...

    Authors: Christoph Vogelbacher, Jens Sommer, Verena Schuster, Miriam H. A. Bopp, Irina Falkenberg, Philipp S. Ritter, Felix Bermpohl, Catherine Hindi Attar, Lisa Rauer, Karolin E. Einenkel, Jens Treutlein, Oliver Gruber, Georg Juckel, Vera Flasbeck, Christoph Mulert, Martin Hautzinger…
    Citation: International Journal of Bipolar Disorders 2021 9:37
    Content type: Study Protocols Published on:

  19. Depending on the classification system used, 5–40% of manic subjects present with concomitant depressive symptoms. This post-hoc analysis evaluates the hypothesis that (hypo)manic subjects have a higher burden...

    Authors: Christoph Born, Heinz Grunze, Robert M. Post, Lori L. Altshuler, Ralph Kupka, Susan L. McElroy, Mark A. Frye, Trisha Suppes, Paul E. Keck, Willem A. Nolen and Lars Schaerer
    Citation: International Journal of Bipolar Disorders 2021 9:36
    Content type: Research Published on:

  20. Although it has been suggested that pregnancy may influence the course of bipolar disorder (BD), studies show contradictory results. Until now, no studies included a finegrained validated method to report mood...

    Authors: Anja W. M. M. Stevens, Stasja Draisma, Peter J. J. Goossens, Birit F. P. Broekman, Adriaan Honig, Elise A. M. Knoppert-van der Klein, Willem A. Nolen, Robert M. Post and R. W. Kupka
    Citation: International Journal of Bipolar Disorders 2021 9:35
    Content type: Research Published on:

  21. Affective lability is elevated and associated with increased clinical burden in psychosis spectrum disorders. The extent to which the level, structure and dispersion of affective lability varies between the sp...

    Authors: Margrethe Collier Høegh, Ingrid Melle, Sofie R. Aminoff, Beathe Haatveit, Stine Holmstul Olsen, Idun B. Huflåtten, Torill Ueland and Trine Vik Lagerberg
    Citation: International Journal of Bipolar Disorders 2021 9:34
    Content type: Research Published on:

  22. The early pathogenesis and precursors of Bipolar Disorder (BD) are poorly understood. There is some cross-sectional and retrospective evidence of affective lability as a predictor of BD, but this is subject to...

    Authors: Rosie H. Taylor, Andrea Ulrichsen, Allan H. Young and Rebecca Strawbridge
    Citation: International Journal of Bipolar Disorders 2021 9:33
    Content type: Review Published on:

  23. We aimed to investigate the outcome of postpartum psychosis over a four-year follow-up, and to identify potential clinical markers of mood/psychotic episodes outside of the postpartum period.

    Authors: Anna-Sophie Rommel, Nina Maren Molenaar, Janneke Gilden, Steven A. Kushner, Nicola J. Westerbeek, Astrid M. Kamperman and Veerle Bergink
    Citation: International Journal of Bipolar Disorders 2021 9:31
    Content type: Research Published on:

  24. Authors: Jan Scott, Florence Vorspan, Josephine Loftus, Frank Bellivier and Bruno Etain
    Citation: International Journal of Bipolar Disorders 2021 9:32
    Content type: Correction Published on:

    The original article was published in International Journal of Bipolar Disorders 2021 9:29

  25. Understanding the underlying architecture of mood regulation in bipolar disorder (BD) is important, as we are starting to conceptualize BD as a more complex disorder than one of recurring manic or depressive e...

    Authors: Abigail Ortiz, Kamil Bradler, Maxine Mowete, Stephane MacLean, Julie Garnham, Claire Slaney, Benoit H. Mulsant and Martin Alda
    Citation: International Journal of Bipolar Disorders 2021 9:30
    Content type: Research Published on:

  26. Major contributors to the global burden of bipolar disorders (BD) are the early age at onset (AAO) and the co-occurrence of non-mood disorders before and after the onset of BD. Using data from two independent ...

    Authors: Jan Scott, Florence Vorspan, Josephine Loftus, Frank Bellivier and Bruno Etain
    Citation: International Journal of Bipolar Disorders 2021 9:29
    Content type: Research Published on:

    The Correction to this article has been published in International Journal of Bipolar Disorders 2021 9:32

  27. There is increasing evidence that bipolar disorder is influenced by circadian timing, including the timing of sleep and waking activities. Previous studies in bipolar disorder have shown that people with later...

    Authors: Parisa Vidafar, Anastasia K. Yocum, Peisong Han, Melvin G. McInnis and Helen J. Burgess
    Citation: International Journal of Bipolar Disorders 2021 9:28
    Content type: Research Published on:

  28. Although valproic acid (VPA) induces the metabolism of multiple other drugs, the clinical reports of VPA autoinduction are rare. A comprehensive literature search yielded only one published case series, which ...

    Authors: Sean Bennett and Mujeeb U. Shad
    Citation: International Journal of Bipolar Disorders 2021 9:27
    Content type: Review Published on:

  29. Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts w...

    Authors: Michael Bauer, Tasha Glenn, Eric D. Achtyes, Martin Alda, Esen Agaoglu, Kürşat Altınbaş, Ole A. Andreassen, Elias Angelopoulos, Raffaella Ardau, Edgar Arrua Vares, Memduha Aydin, Yavuz Ayhan, Christopher Baethge, Rita Bauer, Bernhard T. Baune, Ceylan Balaban…
    Citation: International Journal of Bipolar Disorders 2021 9:26
    Content type: Research Published on:

  30. The current study evaluated the long-term (52 week) safety and impact on symptom measures of lurasidone (with or without lithium or valproate) for the treatment of bipolar I disorder in Japanese patients.

    Authors: Teruhiko Higuchi, Tadafumi Kato, Mari Miyajima, Kei Watabe, Takahiro Masuda, Katsuhiko Hagi and Jun Ishigooka
    Citation: International Journal of Bipolar Disorders 2021 9:25
    Content type: Research Published on:

  31. Research with the BDSx (Bipolar Disorder Symptom Scale) suggests a 4-factor structure of responses: two depression (cognitive, somatic) and two hypo/mania factors (elation/loss of insight, affrontive symptoms). T...

    Authors: Norm O’Rourke, Andrew Sixsmith, Tal Michael and Yaacov G. Bachner
    Citation: International Journal of Bipolar Disorders 2021 9:24
    Content type: Research Published on:

  32. Early identification and intervention of individuals with risk factors for or subtle prodromal symptoms of bipolar disorders (BD) may improve the illness course and prevent adverse long-term consequences.

    Authors: Julia Martini, Karolina Leopold, Steffi Pfeiffer, Christina Berndt, Anne Boehme, Veit Roessner, Paolo Fusar-Poli, Allan H. Young, Christoph U. Correll, Michael Bauer and Andrea Pfennig
    Citation: International Journal of Bipolar Disorders 2021 9:23
    Content type: Research Published on:

  33. Bipolar disorder onset peaks over early adulthood and confirmed family history is a robust risk factor. However, penetrance within families varies and most children of bipolar parents will not develop the illn...

    Authors: Alysha Cooper, Julie Horrocks, Sarah Goodday, Charles Keown-Stoneman and Anne Duffy
    Citation: International Journal of Bipolar Disorders 2021 9:22
    Content type: Research Published on:

  34. A subgroup of those with bipolar spectrum disorders experience ongoing mood fluctuations outside of full episodes. We conducted a randomised, controlled feasibility study of a Dialectical Behavioural Therapy-i...

    Authors: Kim Wright, Alyson L. Dodd, Fiona C. Warren, Antonieta Medina-Lara, Barnaby Dunn, Julie Harvey, Mahmood Javaid, Steven H. Jones, Christabel Owens, Rod S. Taylor, Deborah Duncan, Alexandra Newbold, Shelley Norman, Faith Warner and Thomas R. Lynch
    Citation: International Journal of Bipolar Disorders 2021 9:20
    Content type: Research Published on:

  35. ‘Pediatric bipolar disorder’ (PBD) is a controversial diagnosis with varying rates of clinical diagnosis. A highly cited meta-analysis (Van Meter et al. 2011) of a dozen epidemiological surveys suggested a glo...

    Authors: Peter Parry, Stephen Allison and Tarun Bastiampillai
    Citation: International Journal of Bipolar Disorders 2021 9:21
    Content type: Research Published on:

  36. Despite an increasing number of available mental health apps in the bipolar disorder field, these tools remain scarcely implemented in everyday practice and are quickly discontinued by patients after downloadi...

    Authors: Marie-Camille Patoz, Diego Hidalgo-Mazzei, Bruno Pereira, Olivier Blanc, Ingrid de Chazeron, Andrea Murru, Norma Verdolini, Isabella Pacchiarotti, Eduard Vieta, Pierre-Michel Llorca and Ludovic Samalin
    Citation: International Journal of Bipolar Disorders 2021 9:19
    Content type: Review Published on:

  37. Lithium is the best documented maintenance treatment in bipolar disorder, but its use varies considerably across and within countries. It is not known whether regional differences in lithium prescription rates...

    Authors: Martin Sköld, Sindre Rolstad, Erik Joas, Mathias Kardell, Erik Pålsson, Guy M. Goodwin and Mikael Landén
    Citation: International Journal of Bipolar Disorders 2021 9:18
    Content type: Research Published on:

  38. The coronavirus disease (COVID-19) pandemic, a global health crisis, has resulted in widespread socioeconomic restrictions including lockdown, social distancing, and self-isolation. To date, little is known ab...

    Authors: Nina Dalkner, Jolana Wagner-Skacel, Michaela Ratzenhofer, Frederike Fellendorf, Melanie Lenger, Alexander Maget, Adelina Tmava-Berisha, René Pilz, Robert Queissner, Carlo Hamm, Susanne Bengesser, Martina Platzer, Armin Birner and Eva Reininghaus
    Citation: International Journal of Bipolar Disorders 2021 9:16
    Content type: Research Published on:

  39. Phenotypic heterogeneity is a major impediment to the elucidation of the neurobiology and genetics of bipolar disorder. Endophenotype could help in reducing heterogeneity by defining biological traits that are...

    Authors: Riccardo Guglielmo, Kamilla Woznica Miskowiak and Gregor Hasler
    Citation: International Journal of Bipolar Disorders 2021 9:17
    Content type: Review Published on:

  40. This study aimed to compile and synthesize studies investigating explicit emotion regulation in patients with bipolar disorder and individuals at risk of developing bipolar disorder. The importance of explicit...

    Authors: Marcel Kurtz, Pia Mohring, Katharina Förster, Michael Bauer and Philipp Kanske
    Citation: International Journal of Bipolar Disorders 2021 9:15
    Content type: Review Published on:

  41. DSM-IV states that criterion A for diagnosing hypomania/mania is mood change. The revised DSM-5 now states that increased energy or activity must be present alongside mood changes to diagnose hypomania/mania, ...

    Authors: Mette U. Fredskild, Sharleny Stanislaus, Klara Coello, Sigurd A. Melbye, Hanne Lie Kjærstad, Kimie Stefanie Ormstrup Sletved, Trisha Suppes, Maj Vinberg and Lars Vedel Kessing
    Citation: International Journal of Bipolar Disorders 2021 9:14
    Content type: Research Published on:

  42. The Stanley Foundation Bipolar Treatment Outcome Network (SFBN) recruited more than 900 outpatients from 1995 to 2002 from 4 sites in the United States (US) and 3 in the Netherlands and Germany (abbreviated as...

    Authors: Robert M. Post, Lori L. Altshuler, Ralph Kupka, Susan L. McElroy, Mark A. Frye, Heinz Grunze, Trisha Suppes, Paul E. Keck Jr and Willem A. Nolen
    Citation: International Journal of Bipolar Disorders 2021 9:13
    Content type: Review Published on:

  43. Impaired working memory is a core cognitive deficit in both bipolar disorder and schizophrenia. Its study might yield crucial insights into the underpinnings of both disorders on the cognitive and neurophysiol...

    Authors: Catherine V. Barnes-Scheufler, Caroline Passow, Lara Rösler, Jutta S. Mayer, Viola Oertel, Sarah Kittel-Schneider, Silke Matura, Andreas Reif and Robert A. Bittner
    Citation: International Journal of Bipolar Disorders 2021 9:12
    Content type: Research Published on:

  44. Internet of Things (IoT) devices for remote monitoring, diagnosis, and treatment are widely viewed as an important future direction for medicine, including for bipolar disorder and other mental illness. The nu...

    Authors: Scott Monteith, Tasha Glenn, John Geddes, Emanuel Severus, Peter C. Whybrow and Michael Bauer
    Citation: International Journal of Bipolar Disorders 2021 9:11
    Content type: Review Published on:

  45. Lithium is considered the gold standard treatment for bipolar disorder (BD). Current clinical guidelines and scientific evidence support its use as a first-line treatment in BD. However, over the last two deca...

    Authors: Xabier Pérez de Mendiola, Diego Hidalgo-Mazzei, Eduard Vieta and Ana González-Pinto
    Citation: International Journal of Bipolar Disorders 2021 9:10
    Content type: Research Published on:

  46. Prefrontal dopamine D1 receptor (D1R) mediates behavior related to anxiety, reward and memory, and is involved in inflammatory processes, all of which are affected in bipolar disorder. Interleukin-6 (IL-6), a ...

    Authors: Dominik K. E. Beyer, Annika Mattukat and Nadja Freund
    Citation: International Journal of Bipolar Disorders 2021 9:9
    Content type: Research Published on:

  47. The Cortisol Awakening Response (CAR) measured as the transient increase in cortisol levels following morning awakening appears to be a distinct feature of the HPA axis. Patients with bipolar disorder (BD) exp...

    Authors: Maria Faurholt-Jepsen, Vibe Gedsø Frøkjær, Arafat Nasser, Niklas Rye Jørgensen, Lars Vedel Kessing and Maj Vinberg
    Citation: International Journal of Bipolar Disorders 2021 9:8
    Content type: Research Published on:

  48. Visible light, predominantly in the blue range, affects mood and circadian rhythm partly by activation of the melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). The light-induc...

    Authors: Helle Østergaard Madsen, Shakoor Ba-Ali, Steffen Heegaard, Ida Hageman, Ulla Knorr, Henrik Lund-Andersen, Klaus Martiny and Lars Vedel Kessing
    Citation: International Journal of Bipolar Disorders 2021 9:7
    Content type: Research Published on:

  49. Bipolar disorder is a severe psychiatric illness with poor prognosis and problematic and suboptimal treatments. Understanding the pathoetiologic mechanisms may improve treatment and outcomes.

    Authors: Rif S. El-Mallakh, Yonglin Gao and Pan You
    Citation: International Journal of Bipolar Disorders 2021 9:6
    Content type: Review Published on:

  50. In vitro studies have demonstrated that lithium has antiviral properties, but evidence from human studies is scarce. Lithium is used as a mood stabilizer to treat patients with bipolar disorder. Here, the aim ...

    Authors: Mikael Landén, Henrik Larsson, Paul Lichtenstein, Johan Westin and Jie Song
    Citation: International Journal of Bipolar Disorders 2021 9:4
    Content type: Research Published on:
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