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International Journal of Bipolar Disorders

Table 5 Most frequent stable combinations by specific drug ( N = 353)

From: Drug treatment patterns in bipolar disorder: analysis of long-term self-reported data

Combinations by drug

Number of patients

Monotherapy

 

   Lithium

21

   Lamotrigine

20

   Valproate

17

   Bupropion

4

   Quetiapine

4

   Oxcarbazepine

3

   Citalopram

2

   Clonazepam

2

   Paroxetine

2

   Olanzapine

2

Two drugs

 

   Lithium + lamotrigine

8

   Lamotrigine + quetiapine

5

   Lamotrigine + venlafaxine

5

   Valproate + bupropion

4

   Lamotrigine + clonazepam

4

   Lithium + quetiapine

4

   Valproate + lamotrigine

3

   Lamotrigine + bupropion

3

   Lamotrigine + citalopram

3

   Lamotrigine + risperidone

3

   Oxcarbazepine + fluoxetine

3

   Oxcarbazepine + quetiapine

3

   Bupropion + escitalopram

2

   Carbamazepine + citalopram

2

   Carbamazepine + lamotrigine

2

   Valproate + quetiapine

2

   Valproate + sertraline

2

   Lamotrigine + fluvoxamine

2

   Lamotrigine + escitalopram

2

   Lamotrigine + fluoxetine

2

   Lithium + venlafaxine

2

   Lithium + olanzapine

2

   Fluoxetine + olanzapine

2

   Oxcarbazepine + bupropion

2

   Venlafaxine + aripiprazole

2

Three drugs

 

   Lamotrigine + clonazepam + quetiapine

2

   Lamotrigine + venlafaxine + clonazepam

2

   Lithium + carbamazepine + olanzapine

2

   Lithium + lamotrigine + clonazepam

2

   Lithium + lamotrigine + quetiapine

2

   Lithium + lamotrigine + olanzapine

2

Four or more drugs

 

   Lithium + lamotrigine + clonazepam + quetiapine

2

   Lamotrigine + bupropion + paroxetine + quetiapine + aripiprazole

2

  1. Only combinations taken by more than one patient included. Data from 167 (47%) of 353 patients and 43 (19%) of 231 unique combinations by drug.
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