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Table 5 Most frequent stable combinations by specific drug ( N = 353)

From: Drug treatment patterns in bipolar disorder: analysis of long-term self-reported data

Combinations by drug Number of patients
Monotherapy  
   Lithium 21
   Lamotrigine 20
   Valproate 17
   Bupropion 4
   Quetiapine 4
   Oxcarbazepine 3
   Citalopram 2
   Clonazepam 2
   Paroxetine 2
   Olanzapine 2
Two drugs  
   Lithium + lamotrigine 8
   Lamotrigine + quetiapine 5
   Lamotrigine + venlafaxine 5
   Valproate + bupropion 4
   Lamotrigine + clonazepam 4
   Lithium + quetiapine 4
   Valproate + lamotrigine 3
   Lamotrigine + bupropion 3
   Lamotrigine + citalopram 3
   Lamotrigine + risperidone 3
   Oxcarbazepine + fluoxetine 3
   Oxcarbazepine + quetiapine 3
   Bupropion + escitalopram 2
   Carbamazepine + citalopram 2
   Carbamazepine + lamotrigine 2
   Valproate + quetiapine 2
   Valproate + sertraline 2
   Lamotrigine + fluvoxamine 2
   Lamotrigine + escitalopram 2
   Lamotrigine + fluoxetine 2
   Lithium + venlafaxine 2
   Lithium + olanzapine 2
   Fluoxetine + olanzapine 2
   Oxcarbazepine + bupropion 2
   Venlafaxine + aripiprazole 2
Three drugs  
   Lamotrigine + clonazepam + quetiapine 2
   Lamotrigine + venlafaxine + clonazepam 2
   Lithium + carbamazepine + olanzapine 2
   Lithium + lamotrigine + clonazepam 2
   Lithium + lamotrigine + quetiapine 2
   Lithium + lamotrigine + olanzapine 2
Four or more drugs  
   Lithium + lamotrigine + clonazepam + quetiapine 2
   Lamotrigine + bupropion + paroxetine + quetiapine + aripiprazole 2
  1. Only combinations taken by more than one patient included. Data from 167 (47%) of 353 patients and 43 (19%) of 231 unique combinations by drug.