Table 2 Patient baseline characteristics by level of compliance
High (≥80%) | Low (<80%) | pvalue | |
|---|---|---|---|
Demographics | |||
Age, years, mean (SD) | 43.0 (12.8) | 43.8 (12.9) | 0.44 |
Weight, kg, mean (SD) | 73.5 (13.8) | 73.9 (14.1) | 0.69 |
Height, cm, mean (SD) | 168.1 (9.3) | 167.1 (8.8) | 0.11 |
Sex, females, n (%) | 337 (56.7) | 176 (59.3) | 0.47 |
Race, n (%) | 0.30 | ||
Caucasian | 384 (65.1) | 198 (67.3) | |
Hispanic | 37 (6.3) | 24 (8.2) | |
East Asian | 169 (28.6) | 72 (24.5) | |
Clinical characteristics | |||
CGI-S, mean (SD) | 2.4 (0.7) | 2.6 (0.7) | 0.002 |
DAI-10, mean (SD) | 5.7 (3.7) | 4.8 (4.0) | 0.002 |
Days bipolar inpatient last year, mean (SD) | 15.4 (38.5) | 18.4 (32.8) | 0.029 |
Recent relapse, n (%) | 68 (11.4) | 68 (22.9) | <0.001 |
Functional characteristics | |||
EQ-5D overall health status score (SD) | 0.9 (0.2) | 0.8 (0.2) | 0.0012 |
EQ-5D VAS score (SD) | 74.2 (15.4) | 69.6 (17.6) | <0.001 |
Number of activities with friends or social groups, n (%) | |||
0 | 100 (16.8) | 85 (29.0) | |
1 | 66 (11.1) | 40 (13.7) | <0.001 |
2 | 117 (19.7) | 49 (16.7) | |
3 | 78 (13.1) | 40 (13.7) | |
4 | 70 (11.8) | 20 (6.8) | |
≥5 | 163 (27.4) | 59 (20.1) | |
Work activity, n (%) | |||
Unable to work | 34 (5.8) | 26 (9.0) | <0.001 |
Volunteer work | 21 (3.6) | 6 (2.1) | |
Student | 34 (5.8) | 12 (4.1) | |
Working for pay | 199 (33.8) | 76 (26.2) | |
Keeping house | 109 (18.5) | 48 (16.6) | |
Unemployed | 59 (10.0) | 23 (7.9) | |
Sheltered program | 15 (2.5) | 3 (1.0) | |
Retired | 118 (20.0) | 96 (33.1) | |
Impairment in work activities, n (%) | |||
No impairment | 123 (20.8) | 39 (13.3) | |
Mild impairment | 220 (37.2) | 81 (27.6) | |
Moderate impairment | 150 (25.4) | 133 (45.2) | |
Severe impairment | 50 (8.5) | 22 (7.5) | |
Unable to work due to mental illness | 31 (5.2) | 15 (5.1) | <0.001 |
Patient-physician relationship, n (%) | |||
Poor | 0 | 7 (2.4) | <0.001 |
Fair | 20 (3.4) | 25 (8.4) | |
Good | 158 (26.6) | 148 (49.8) | |
Very good | 277 (46.6) | 101 (34.0) | |
Excellent | 139 (23.4) | 16 (5.4) | |
Insight into illness, n (%) | |||
None | 3 (0.5) | 3 (1.0) | |
Low | 26 (4.4) | 49 (16.5) | <0.001 |
Medium | 87 (14.6) | 111 (37.4) | |
Moderate | 168 (28.3) | 93 (31.3) | |
High | 310 (52.2) | 41 (13.8) | |
Length of previous treatment regimen (4 weeks before baseline, containing olanzapine), n (%) | |||
<14 days | 8 (1.3) | 10 (3.5) | |
15 to 30 days | 125 (21.1) | 91 (31.5) | <0.001 |
31 to 90 days | 212 (35.8) | 77 (26.6) | |
>90 days | 244 (41.1) | 101 (34.9) |