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Table 4 Point estimates and confidence intervals for the expected depression score SUMD at week 12 under static regimes (first-line treatment, second-line treatment) and estimated DTR

From: Who will benefit from antidepressants in the acute treatment of bipolar depression? A reanalysis of the STEP-BD study by Sachs et al. 2007, using Q-learning

Regime ( π 1 , π 2 )

Estimated

90% Confidence

 

SUMD

interval

Estimated DTR

2.13

(1.34, 2.86)

(Bupropion, high-dose Bupropion)

6.91

(6.27, 7.71)

(Paroxetine, high-dose Paroxetine)

8.25

(7.39, 9.07)

(placebo, high-dose Bupropion)

3.71

(3.38, 4.04)

(placebo, high-dose Paroxetine)

4.51

(4.10, 4.90)