Table 5 Candidate predictors for regression models in Q -learning

Age

Age at entry (years)

AGE

Numerical

18–77

40.59 (11.74)

Race

Race

RACE

Binary

White or Causasian, non-White

90.4%, 9.6%

Gender

Gender

GENDER

Trinary

Male, female, transgender

43%, 56%, 1%

Marriage

Marital status

MARSTAT

Trinary

Never married, married,

35.6%, 33.8%, 30.6%

separated

Household Income

Annual household income

HINCOME

Binary

<40, ≥40

58.5%, 41.5%

(×$1000)

Employment

Employment status

EMPLOY

Binary

Employed, unemployed

46.9%, 53.1%

Education

Education level

EDUCATE

Binary

College or below, technical

53%, 47%

school or above

Insurance

Indicator of medical insurance

MEDINS

Binary

Yes, no

72.8%, 27.2%

Bipolar Type

Bipolar type at entry

BITYPE

Binary

Type I, type II

70.4%, 29.6%

Prior Episode

Clinical episode immediately

PRONSET

Trinary

Remission, (hypo)manic,

45.9%, 33.2%, 20.9%

preceding current depressive

mixed

episode

SUMD0

Scaled depression at entry

SUMD0

Numerical

0.75–18

7.47 (2.30)

SUMD1 ^a

Scaled depression at the end

SUMD1

Numerical

0–14

4.49 (3.07)

of stage 1

SUMM0

Scaled mood elevation at entry

SUMM0

Numerical

0–7

1.19 (1.09)

SUMM1 ^a

Scaled mood elevation at the

SUMM1

Numerical

0–6.75

0.95 (1.30)

end of stage 1

Treatment 1 ^a

Treatment received at stage 1

Trt1

Trinary

Bupropion, Paroxetine,

23.3%, 25.5%, 51.2%

placebo

Side 1

Tremor

SIDE1

Binary

Yes, no

26.9%, 73.1%

Side 2

Dry mouth

SIDE2

Binary

Yes, no

21.1%, 78.9%

Side 3

Sedation

SIDE3

Binary

Yes, no

17.1%, 82.9%

Side 4

Constipation

SIDE4

Binary

Yes, no

5.7%, 94.3%

Side 5

Diarrhea

SIDE5

Binary

Yes, no

12%, 88%

Side 6

Headache

SIDE6

Binary

Yes, no

13.7%, 86.3%

Side 7

Poor memory

SIDE7

Binary

Yes, no

14.3%, 85.7%

Side 8

Sexual dysfunction

SIDE8

Binary

Yes, no

9.7%, 90.3%

Side 9

Increased appetite

SIDE9

Binary

Yes, no

12.6%, 87.4%