Table 2 Clinical characteristics of participants in the bipolar disorder biobank (n = 1363)
Characteristic | Valuea |
|---|---|
SCID diagnosis | |
Bipolar I | 941 (69.0) |
Bipolar II | 398 (29.2) |
Schizoaffective bipolar | 24 (1.8) |
Current or recent depression | 679 (49.8) |
History of psychosis | 563 (42.3) |
(n = 1330) | |
Suicide attempt | 436 (32.5) |
(n = 1340) | |
Mood instability | |
Mean value | 1.5 (1.4) |
(n = 1333) | |
Mixed mania | 134 (14.0) |
(n = 954) | |
Rapid cycling | 699 (52.0) |
(n = 1343) | |
Ultrarapid | 379 (28.3) |
(n = 1338) | |
Cycle acceleration | 353 (26.5) |
(n = 1330) | |
Increased severity | 446 (33.4) |
(n = 1336) | |
Anxiety disorder | |
Mean value | 1.5 (1.4) |
(n = 1333) | |
Posttraumatic stress disorder | 345 (26.4) |
(n = 1307) | |
Generalized anxiety disorder | 664 (50.7) |
(n = 1309) | |
Social anxiety disorder | 319 (24.6) |
(n = 1297) | |
Obsessive-compulsive disorder | 192 (14.7) |
(n = 1309) | |
Phobia | 131 (10.1) |
(n = 1301) | |
Panic disorder | 409 (31.3) |
(n = 1306) | |
Addiction, lifetime | |
Mean value | 1.0 (1.0) |
(n = 1342) | |
Alcohol abuse/dependence | 514 (39.1) |
(n = 1316) | |
Nicotine dependence | 522 (39.8) |
(n = 1313) | |
History of drug/substance | 343 (27.0) |
(n = 1271) | |
BMI | (n = 1257) |
Mean value, kg/m2 | 29.91 (6.95) |
Overweight | 397 (31.6) |
Obese | 421 (33.5) |
Morbid obesity | 118 (9.4) |
First-degree relative suicide | 125 (11.7) |
(n = 1067) | |
Antidepressant-induced mania | 247 (31.7) |
(n = 779) | |
Tardive dyskinesia | 37 (3.2) |
(n = 1167) | |
Drug-related rash | 65 (5.7) |
(n = 1147) | |
Serious rash | 9 (3.7) |
(n = 246) |