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Table 6 Difference in bipolar depression and mood elevation scores during the menopausal transition based on history of reproductive phase mood exacerbation

From: Symptom severity of bipolar disorder during the menopausal transition

Reproductive group

Reproductive phase mood exacerbation (by woman), N (%)

Mean MADRS ± SD

t test

p value

Mean YMRS ± SD

t test

p value

Perimenstrual

       

N women = 55

       

History of perimenstrual mood exacerbation

47 (85)

15.4 ± 8.5

t = 0.20

p = 0.85

9.0 ± 6.1

t = −0.59

p = 0.56

No history of perimenstrual mood exacerbation

8 (15)

16.1 ± 14.8

  

7.6 ± 7.2

  

Postpartum

       

N women = 46

       

History of postpartum mood exacerbation

23 (64)

14.4 ± 7.9

t = 0.33

p = 0.74

11.2 ± 5.5

t = −1.91

p = 0.07

No history of postpartum mood exacerbation

13 (36)

15.5 ± 10.8

  

7.2 ± 7.0

  

Perimenstrual and postpartum

       

(N women = 46)

       

Both: history of postpartum and perimenstrual mood exacerbation

20 (91)

14.3 ± 8.0

t = 0.97

p = 0.34

10.9 ± 5.8

t = −0.75

p = 0.46

Neither: no history of postpartum or perimenstrual mood exacerbation

2 (9)

21.0 ± 22.6

  

7.5 ± 10.6

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