From: Symptom severity of bipolar disorder during the menopausal transition
Reproductive group | Reproductive phase mood exacerbation (by woman), N (%) | Mean MADRS ± SD | t test | p value | Mean YMRS ± SD | t test | p value |
---|---|---|---|---|---|---|---|
Perimenstrual | Â | Â | Â | Â | Â | Â | Â |
N women = 55 |  |  |  |  |  |  |  |
History of perimenstrual mood exacerbation | 47 (85) | 15.4 ± 8.5 | t = 0.20 | p = 0.85 | 9.0 ± 6.1 | t = −0.59 | p = 0.56 |
No history of perimenstrual mood exacerbation | 8 (15) | 16.1 ± 14.8 |  |  | 7.6 ± 7.2 |  |  |
Postpartum | Â | Â | Â | Â | Â | Â | Â |
N women = 46 |  |  |  |  |  |  |  |
History of postpartum mood exacerbation | 23 (64) | 14.4 ± 7.9 | t = 0.33 | p = 0.74 | 11.2 ± 5.5 | t = −1.91 | p = 0.07 |
No history of postpartum mood exacerbation | 13 (36) | 15.5 ± 10.8 |  |  | 7.2 ± 7.0 |  |  |
Perimenstrual and postpartum | Â | Â | Â | Â | Â | Â | Â |
(N women = 46) |  |  |  |  |  |  |  |
Both: history of postpartum and perimenstrual mood exacerbation | 20 (91) | 14.3 ± 8.0 | t = 0.97 | p = 0.34 | 10.9 ± 5.8 | t = −0.75 | p = 0.46 |
Neither: no history of postpartum or perimenstrual mood exacerbation | 2 (9) | 21.0 ± 22.6 |  |  | 7.5 ± 10.6 |  |  |