Table 3 Case reports of autoimmune thyroiditis associated with mood disorder

Schmidt et al. (1990)

Menstrual related mood disorder

F 37

12.1

AbM 1/1600 (<1/100)

AbTG 1/10 (<1/10)

Levothyroxine

Bokhari et al. (1998)

Postpartum psychosis

F 29

<0.03

AbTPO 2330 (0–100)

AbTG 597 (0–100)

Loxapine, amoxapine, propranolol, propylthiouracil

Mahmud et al. (2003)

Psychotic depression

F 14

77.4

AbTPO 6320 (0–20)

Psychotropic medication as before (valproate, sertraline, quetiapine) plus levothyroxine, methylprednisolone

Müssig et al. (2005)

Manic episode

F 32

<0.03

AbTPO 2010 (0–2)

AbTG 1.1 (0–1)

Psychotropic medication as before (quetiapine, lithium, mirtazapine, venlafaxine) plus reboxetine and transcranial magnetic stimulation, carbimazole, prednisolone

Laske et al. (2005)

Severe depressive episode

F 74

Normal

AbTPO 842 (0–2)

Prednisolone, venlafaxine as before

Stowell and Barnhill (2005)

Postpartum psychotic acute mania

F 35

>150

AbTPO significantly elevated

Levothyroxine and risperidone

Tor et al. (2007)

Late-onset psychotic mania

F 72

79.4

AbTPO 50 (0–50)

AbTG 2507 IU/ml (0–40)

Levothyroxine and low-dose haloperidol

Bocchetta et al. (2007b)

Affective psychosis

F 43

1.24

AbTPO>1000 (0–35)

AbTG normal

Levothyroxine as before, valproate discontinuation, lithium plus olanzapine

Nagamine et al. (2008)

Lithium-induced encephalopathy

F 61

2.15

AbTPO 50 (0–0.3)

AbTG 1/25,600 (1/100)

Methylprednisolone, levothyroxine as before, lithium discontinuation

Liu et al. (2011)

Acute depressive episode

M 46

66.7

AbTPO 1698 (0–5.61)

AbTG 154 IU/ml (0–14.4)

Levothyroxine, methylprednisolone

Lin et al. (2011)

Manic symptoms

F 52

50.71

AbTPO 1652 (0–25)

AbTG 296 IU/ml (0–25)

Levothyroxine, prednisolone, olanzapine and valproate

Lin et al. (2013)

Acute mania

F 41

18.79

AbTPO 411 (0–60)

AbTG 296 IU/ml (0–60)

Levothyroxine, valproate and quetiapine