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Table 1 Clinical and demographic characteristics of bipolar and control subjects

From: Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene–environment interaction study

 

BD (n = 138)

HC (n = 167)

p value

Mean ± SD

 Age at inclusion (years)

43.6 ± 13.50

39.5 ± 13.77

0.009

 Age at onset (years) (n = 135)a

26.3 ± 10.51

n (%)

 Gender (female)

71 (51.4)

90 (53.9)

0.671

Diagnoses (DSM-VI)

 BD-I

98 (71.0)

 BD-II

37 (26.8)

 BD-NOS

3 (2.2)

Place of birth (Metropolitan France)

113 (81.9)

137 (82.0)

0.973

Education level (higher education)

78 (56.5)

72 (43.1)

0.020

Working status (currently active)

72 (52.2)

93 (55.7)

0.540

Serum anti-pathogen IgG (positive)

Toxoplasma gondii

103 (74.6)

97 (58.1)

0.002

 CMV

84 (60.9)

107 (64.1)

0.565

 HSV-1

34 (24.6)

47 (28.1)

0.490

 HSV-2

87 (63.0)

119 (71.3)

0.127

  1. BD bipolar disorder; HC healthy controls; NOS not otherwise specified; SD standard deviation; CMV cytomegalovirus; HSV-1 herpes simplex virus 1; HSV-2 herpes simplex virus 2; NS non-significant
  2. aData were missing for three patients