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Table 3 TLR2, TLR4 and NOD2 polymorphisms in bipolar patients and healthy controls: genotype distribution

From: Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene–environment interaction study

Polymorphism

 

MAF

p value

HWE p value

BD (n = 138)

Controls (n = 167)

TLR2 rs4696480

T > A

0.46

0.51

0.178

0.929

TLR2 rs3804099

T > C

0.46

0.44

0.610

0.804

TLR4 rs1927914

A > G

0.41

0.39

0.601

0.671

TLR4 rs11536891

T > C

0.17

0.14

0.265

0.588

NOD2 rs2066842

C > T

0.25

0.25

0.898

0.656

  1. TLR2 Toll-like receptor 2; TLR4 Toll-like receptor 4; NOD2 nucleotide-binding oligomerization domain containing 2; BD bipolar disorder; NS non-significant; MAF minor allele frequency; HWE Hardy–Weinberg equilibrium in controls