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International Journal of Bipolar Disorders
Fig. 1 | International Journal of Bipolar Disorders

Fig. 1

From: Current irritability associated with hastened depressive recurrence and delayed depressive recovery in bipolar disorder

Fig. 1

Current irritability associated with hastened depressive recurrence in bipolar disorder. Two-year survival analysis of time to depressive recurrence in recovered bipolar disorder patients indicated significantly hastened depressive recurrence in patients with (N = 38, black line on bottom) vs. without (N = 67, gray line on top) current irritability (Log-Rank p = 0.020). Current irritability was also significantly associated with hastened depressive recurrence using Cox Proportional Hazard analysis (HR = 2.1; 95 % CI 1.1–4.2; p = 0.024). History of anxiety disorder (HR = 3.8, p = 0.002) and prior year rapid cycling (HR = 2.6, p = 0.052) drove and history of psychosis (HR = 0.38, p = 0.023) attenuated hastened depressive recurrence in patients with vs. without current irritability

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