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Table 1 Demographics, illness characteristics, and current mood symptoms in recovered and depressed bipolar disorder outpatients with and without current irritability

From: Current irritability associated with hastened depressive recurrence and delayed depressive recovery in bipolar disorder

  Currently recovered Currently depressed
Current irritability No current irritability Current irritability No current irritability
N (%) 38 (36.2)**** 67 (63.8) 105 (68.6)**** 48 (31.4)
Demographics
 A. Age (years, mean ± SD) 36.3 ± 14.0 35.9 ± 13.6 35.5 ± 13.2 37.8 ± 14.0
 B. Female (%) 60.5 52.2 65.7 52.1
 C. Caucasian (%) 69.4 80.3 87.6 85.4
 D. College degree (%) 64.9 61.5 38.1** 66.7
 E. Married (current, %) 42.1 33.3 38.1 35.4
 F. Full-time employment (current, %) 40.5 30.3 29.5 17.0
Comorbid disorders (lifetime, %)
 1. Anxiety 60.5* 38.8 84.8** 60.4
 2. Alcohol/Substance Use 71.1** 38.8 59.0 56.3
 3. Eating 10.5 9.0 21.9 12.5
 4. Personality 10.5 7.5 18.1 6.3
Other illness characteristics
 5. Bipolar II disorder (%) 57.9** 28.4 69.5** 43.8
 5A. Psychosis (lifetime, %) 31.6 55.2* 32.4 43.8
 5B. Psychiatric hospitalization (lifetime, %) 31.6 55.2* 21.0 37.5*
 6. ≥One 1° degree relative w mood disorder (%) 63.2* 37.3 65.7* 45.8
 7. Onset age (years, mean ± SD) 17.0 ± 8.4* 20.8 ± 8.9 15.6 ± 6.3*** 20.5 ± 9.5
 8. Childhood (age <13 years) onset (%) 21.6 9.0 26.7 14.6
 9. Illness duration (years, mean ± SD) 20.2 ± 16.1 15.8 ± 12.2 19.5 ± 13.8 17.0 ± 11.4
 10. Long illness duration (≥15 years, %) 50.0 46.8 52.9 54.2
 11. Episode accumulation (≥10, lifetime, %) 66.7* 42.4 78.1* 58.7
 12. Suicide attempt (lifetime, %) 44.4** 16.7 32.7 37.5
 13. Rapid cycling (prior year, %) 18.9* 4.8 31.1 25.0
 14. CGI-BP-OS (current, mean ± SD) 2.6 ± 0.6*** 1.9 ± 0.8 5.4 ± 0.8 5.3 ± 0.6
Current mood symptoms (any in prior 10 days, %)
 15. Sadness 31.6* 11.9 89.5 89.6
 16. Anhedonia 23.7* 9.0 95.2 93.8
 17. Euphoria 34.2**** 1.5 34.3* 14.6
 18. Irritability 100.0**** 0.0 100.0**** 0.0
 19. Anxiety 57.9*** 23.9 86.7* 68.8
  1. CGI-BP-OS clinical global impression for bipolar disorder-overall severity, SD standard deviation
  2. p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 with vs.  Underline font indicates parameters with statistically significant relationships with current irritability. Italic font indicates parameters associated with bipolar I subtype. Missing data among recovered patients: 12.4 % for ≥10 prior episodes, 0.0–6.7 % for other parameters. Missing data among depressed patients: 7.2 % for ≥10 prior episodes, 0.0–1.3 % for other parameters