Table 1 Demographics, illness characteristics, and current mood symptoms in recovered and depressed bipolar disorder outpatients with and without current irritability

N (%)

38 (36.2)****

67 (63.8)

105 (68.6)****

48 (31.4)

Demographics

 A. Age (years, mean ± SD)

36.3 ± 14.0

35.9 ± 13.6

35.5 ± 13.2

37.8 ± 14.0

 B. Female (%)

60.5

52.2

65.7

52.1

 C. Caucasian (%)

69.4

80.3

87.6

85.4

 D. College degree (%)

64.9

61.5

38.1**

66.7

 E. Married (current, %)

42.1

33.3

38.1

35.4

 F. Full-time employment (current, %)

40.5

30.3

29.5

17.0

Comorbid disorders (lifetime, %)

 1. Anxiety

60.5*

38.8

84.8**

60.4

 2. Alcohol/Substance Use

71.1**

38.8

59.0

56.3

 3. Eating

10.5

9.0

21.9

12.5

 4. Personality

10.5

7.5

18.1

6.3

Other illness characteristics

 5. Bipolar II disorder (%)

57.9**

28.4

69.5**

43.8

 5A. Psychosis (lifetime, %)

31.6

55.2*

32.4

43.8

 5B. Psychiatric hospitalization (lifetime, %)

31.6

55.2*

21.0

37.5*

 6. ≥One 1° degree relative w mood disorder (%)

63.2*

37.3

65.7*

45.8

 7. Onset age (years, mean ± SD)

17.0 ± 8.4*

20.8 ± 8.9

15.6 ± 6.3***

20.5 ± 9.5

 8. Childhood (age <13 years) onset (%)

21.6

9.0

26.7

14.6

 9. Illness duration (years, mean ± SD)

20.2 ± 16.1

15.8 ± 12.2

19.5 ± 13.8

17.0 ± 11.4

 10. Long illness duration (≥15 years, %)

50.0

46.8

52.9

54.2

 11. Episode accumulation (≥10, lifetime, %)

66.7*

42.4

78.1*

58.7

 12. Suicide attempt (lifetime, %)

44.4**

16.7

32.7

37.5

 13. Rapid cycling (prior year, %)

18.9*

4.8

31.1

25.0

 14. CGI-BP-OS (current, mean ± SD)

2.6 ± 0.6***

1.9 ± 0.8

5.4 ± 0.8

5.3 ± 0.6

Current mood symptoms (any in prior 10 days, %)

 15. Sadness

31.6*

11.9

89.5

89.6

 16. Anhedonia

23.7*

9.0

95.2

93.8

 17. Euphoria

34.2****

1.5

34.3*

14.6

 18. Irritability

100.0****

0.0

100.0****

0.0

 19. Anxiety

57.9***

23.9

86.7*

68.8