From: Aims and structure of the German Research Consortium BipoLife for the study of bipolar disorder
Bipolife project | Subject | Population | N | Design | TPP1 | TPP2 | ||
---|---|---|---|---|---|---|---|---|
Phenotype database | Biomaterials | Neuroimaging | EEG | |||||
A1 | Assessment of factors associated with conversion to bipolar disorder | Young persons at-risk of BD | 1500 | Epidemiological, Follow-up | ✓ | ✓ | ✓ | ✓ |
A2 | Trial of specific group psychotherapy for bipolar disorder | Young patients with recent onset of BD | 300 | Double-blind, randomized, controlled trial | ✓ | ✓ | ✓ | |
A3 | Smartphone-based ambulatory monitoring with threshold based feedback | Patients with a highly recurrent/unstable course of BD | 180 | Rater blind, randomized, parallel group trial | ✓ | |||
B2 | Neuroimaging study in patients with affective disorders and acute suicidality | Patients with severe suicidality | 80 | Double-blind, randomized, placebo-controlled trial | ✓ | ✓ | ||
B3 | Genomic, transcriptomic and proteomic markers of lithium response | BD patients with lithium response vs. non response | 150 | Cross-sectional | ✓ | ✓ |