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Fig. 1 | International Journal of Bipolar Disorders

Fig. 1

From: American tertiary clinic-referred bipolar II disorder versus bipolar I disorder associated with hastened depressive recurrence

Fig. 1

Bipolar II disorder associated with hastened depressive recurrence. Two-year survival analysis of time to depressive recurrence in recovered bipolar disorder patients indicated significantly hastened depressive recurrence in patients with bipolar II disorder (N = 41, black line on bottom) versus bipolar I disorder (N = 64, gray line on top, log-rank, p = 0.015). Bipolar II disorder compared to bipolar I disorder was also significantly associated with hastened depressive recurrence using Cox proportional hazard analysis [hazard ratio (HR) = 2.3 (95% confidence interval (CI) 1.2–4.5), p = 0.018]. Lifetime anxiety disorder (HR = 4.4, 95% CI 1.9–10.5, p = 0.001) drove and lifetime history of psychosis (HR = 0.24, 95% CI 0.088–0.68, p = 0.007) attenuated hastened depressive recurrence in patients with bipolar II disorder versus bipolar I disorder

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