From: Childhood maltreatment and the medical morbidity in bipolar disorder: a case–control study
Bipolar cases, N (%) [N = 72] | Controls, N (%) [N = 354] | Statistic | p value | |
---|---|---|---|---|
Female | 56 (78) | 205 (58) | χ 2(1) = 9.34 | 0.002 |
Age at assessment [mean (SD)] | 48.36 (9.42) | 47.73 (9.15) | t (395) = 0.52 | 0.60 |
At least one medical illness | 42 (58) | 96 (27) | χ 2(1) = 26.61 | <0.001 |
Number of medical illnesses | ||||
None | 30 (42) | 259 (73) | ||
1 | 21 (29) | 78 (22) | ||
2 or more | 21 (29) | 17 (4) | χ 2(2) = 49.88 | <0.001 |
Different types of medical illnesses | ||||
Heart problems (i.e. stroke, angina and heart attack) | 1 (1) | 2 (1) | Two-tailed fisher’s exact | 0.427 |
Asthma | 15 (21) | 31 (9) | χ 2(2) = 9.06 | 0.003 |
Diabetes (types I and II) | 5 (7) | 7 (2) | Two-tailed fisher’s exact | 0.036 |
Arthritis | 17 (24) | 23 (7) | χ 2(2) = 20.60 | <0.001 |
Hypertension | 16 (22) | 32 (9) | χ 2(2) = 10.40 | 0.001 |
Epilepsy or convulsions | 3 (4) | 0 (0) | Two-tailed fisher’s exact | 0.005 |
Osteoporosis | 3 (4) | 3 (0.9) | Two-tailed fisher’s exact | 0.063 |
Multiple sclerosis | 0 (0) | 0 (0) | – | |
Emphysema or chronic bronchitis | 5 (7) | 14 (4) | χ 2(2) = 1.26 | 0.263 |
Postherpetic neuralgia | 0 (0) | 2 (0.6) | Two-tailed fisher’s exact | 1.00 |
Childhood maltreatment | ||||
Any type of childhood maltreatment (abuse and/or neglect)a, b | 37 (51) | 64 (18) | χ 2(1) = 36.70 | <0.001 |
Any type of child abusea, c | 31 (43) | 41 (12) | χ 2(1) = 42.20 | <0.001 |
Physical abuse | 8 (11) | 13 (4) | χ 2(1) = 6.99 | 0.008 |
Emotional abuse | 20 (28) | 23 (7) | χ 2(1) = 35.13 | <0.001 |
Sexual abuse | 20 (28) | 20 (6) | χ 2(1) = 34.16 | <0.001 |
Any type of child neglecta, d | 20 (28) | 36 (10) | χ 2(1) = 16.25 | <0.001 |
Physical neglect | 10 (14) | 64 (6) | χ 2(1) = 5.04 | 0.025 |
Emotional neglect | 19 (26) | 28 (8) | χ 2(1) = 20.71 | <0.001 |