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Table 3 Relationships between mood and cluster analysis-identified chronobiological characteristics

From: The association between mood state and chronobiological characteristics in bipolar I disorder: a naturalistic, variable cluster analysis-based study

Variables YMRS IDS-30-C
Unadjusted correlations
r (p value)
Adjusted linear regression RC (p value) BHC
p value
Unadjusted correlations
r (p value)
Adjusted linear regression RC (p value) BHC
p value
IS − 0.331 (0.0007)* − 0.004 (0.005)* 0.030* 0.0005 (0.995) 0.001 (0.25) 0.956
RA − 0.391 (< 0.0001)* − 0.005 (0.0003)* 0.0021* − 0.064 (0.523) 0.001 (0.268) 0.956
GOF − 0.333 (0.0006)* − 0.003 (0.017)* 0.051a − 0.099 (0.32) − 0.00 (0.956) 0.956
CQ − 0.217 (0.027)* − 0.005 (0.006)* 0.030* 0.057 (0.565) 0.002 (0.181) 0.956
24-h correlation − 0.317 (0.001)* − 0.003 (0.623) 0.623 − 0.152 (0.124) − 0.00 (0.623) 0.956
SRM-5 − 0.218 (0.0325)* − 0.026 (0.09)a 0.180 − 0.038 (0.696) 0.004 (0.741) 0.956
PSQI 0.351 (0.0003)* 0.111 (0.012)* 0.048* 0.396 (< 0.0001)* 0.099 (0.005)* 0.035*
  1. The relationships between mood rating scale scores and variables characterizing biorhythms. Unadjusted correlations as well as linear regression results adjusted for age, gender, and medication class use (lithium, anticonvulsants, antidepressants, antipsychotics, benzodiazepines) are shown. r denotes correlation coefficient and RC denotes regression coefficient
  2. IS interdaily stability, IV intradaily variability, RA relative amplitude, CQ circadian quotient, GOF goodness-of-fit, SRM-5 5-Item Social Rhythm Metric, PSQI Pittsburgh Sleep Quality Index, YMRS Young Mania Rating Scale, IDS-30-C 30-Item Inventory of Depressive Symptomatology. BHC Benjamini–Hochberg Correction for multiple testing
  3. * and italic font denotes statistical significance
  4. aDenotes a trend toward significance