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Table 2 Demographic and clinical characteristics by the patient’s final eGFR category

From: Circulating antithyroid antibodies contribute to the decrease of glomerular filtration rate in lithium-treated patients: a longitudinal study

 

G3b (N = 84)

G3a (N = 55)

G1–G2 (N = 255)

Between-group differences (P value)

Number of males

13 (15%)a

18 (33%)

74 (29%)b

a < b (0.01)

Current age, mean ± SD

59 ± 11c

56 ± 13d

48 ± 21e

c > e (0.0001); d > e (0.007)

Treatment with antihypertensive agents before declining to eGFR < 60 mL/min/1.73 m2

38 (45%)f

22 (40%)

72 (28%)g

f > g (0.005)

Diabetes

21 (25%)

18 (33%)

50 (20%)

Treatment with l-thyroxine

 Males

4 (31%)h

2 (11%)

5 (7%)i

h > i (0.03)

 Females

32 (45%)

14 (38%)

68 (38%)

 

 Total

36 (43%)j

16 (29%)

73 (29%)k

l > m (0.02)

Circulating thyroid antibodies

 Males

4 (31%)l

2 (11%)

6 (8%)m

n > o (0.04)

 Females

29 (41%)

8 (22%)

53 (29%)

 Total

33 (39%)n

10 (18%)

59 (23%)o

p > q (0.005)

  1. Superscripts a–o are used to indicate significant between-group differences
  2. G1–G2, eGFR ≥ 60 mL/min/1.73 m2
  3. G3a, eGFR = 45–59 mL/min/1.73 m2
  4. G3b, eGFR < 45 mL/min/1.73 m2