Table 1 Participant and episode-free run-in period characteristics
Baseline participant characteristics | Short run-in period cohorta N = 146 | Long run-in period cohortb N = 100 |
|---|---|---|
Males, n (%) | 53 (37) | 40 (41)c |
Age, years, mean (SD) | 43.4 (13.3) | 44.5 (13.5) |
White, n (%) | 139 (97) | 94 (96)c |
Education, n (%) | ||
O-level/GCSE or fewer years | 18 (13) | 12 (12) |
A-level/AS levels/Scottish Highers/HND/BTEC | 24 (17) | 17 (18) |
Degree (includes NVQ level 5) | 56 (40) | 35 (36)c |
Post-graduate degree | 43 (30) | 33 (34)c |
Occupation, n (%) | ||
Disabled | 1 (1) | 1 (1)c |
Housewife/homemaker | 9 (6) | 7 (7)c |
Full-time student | 16 (11) | 9 (9)c |
Unemployed | 27 (19) | 16 (17)c |
Retired | 11 (8) | 9 (9)c |
Employed | 76 (54) | 54 (56)c |
Diagnosis, n (%) | ||
Bipolar disorder type I | 80 (58) | 60 (65)c |
Bipolar disorder type II | 53 (38) | 30 (32)c |
Bipolar disorder not otherwise specified | 5 (4) | 3 (3)c |
Depression history | ||
Episodes, median (IQR) | 10 (6–20) | 10 (6–17.5) |
Age of impairment, years, mean (SD) | 21.7 (9.0) | 23.1 (9.8) |
Duration of illness, years, median (IQR) | 19 (10–30) | 18 (10–31) |
Hospital admissions, yes, n (%) | 63 (43) | 41 (41) |
Mania history | ||
Episodes, median (IQR) | 10 (4–20) | 9 (4–15) |
Age of impairment, years, mean (SD) | 27.2 (11.4) | 28.7 (11.7) |
Duration of illness, years, median (IQR) | 13 (6–25) | 12 (6–26) |
Hospital admissions, yes, n (%) | 46 (32) | 33 (33) |
Alcohol use, yes, n (%) | 109 (86) | 71 (85)c |
Smoker, yes, n (%) | 80 (56) | 54 (55)c |
Episode-free run-in period characteristics | ||
Number of prompts, mean (SD) | 9 (1.1) | 22.2 (2) |
Percentage of missing values, mean (SD) | 10 (14) | 13 (14) |
ASRM score across participants | ||
Mean score, mean (SD) | 2.0 (1.6) | 1.8 (1.4) |
Standard deviation of score, mean (SD) | 1.7 (1.0) | 1.6 (0.9) |
QIDS score across participants | ||
Mean score, mean (SD) | 6.2 (2.7) | 5.1 (2.4) |
Standard deviation of score, mean (SD) | 2.5 (1.2) | 2.5 (1.0) |