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Table 1 Participant and episode-free run-in period characteristics

From: Control charts for monitoring mood stability as a predictor of severe episodes in patients with bipolar disorder

Baseline participant characteristics Short run-in period cohorta N = 146 Long run-in period cohortb N = 100
Males, n (%) 53 (37) 40 (41)c
Age, years, mean (SD) 43.4 (13.3) 44.5 (13.5)
White, n (%) 139 (97) 94 (96)c
Education, n (%)
 O-level/GCSE or fewer years 18 (13) 12 (12)
 A-level/AS levels/Scottish Highers/HND/BTEC 24 (17) 17 (18)
 Degree (includes NVQ level 5) 56 (40) 35 (36)c
 Post-graduate degree 43 (30) 33 (34)c
Occupation, n (%)
 Disabled 1 (1) 1 (1)c
 Housewife/homemaker 9 (6) 7 (7)c
 Full-time student 16 (11) 9 (9)c
 Unemployed 27 (19) 16 (17)c
 Retired 11 (8) 9 (9)c
 Employed 76 (54) 54 (56)c
Diagnosis, n (%)
 Bipolar disorder type I 80 (58) 60 (65)c
 Bipolar disorder type II 53 (38) 30 (32)c
 Bipolar disorder not otherwise specified 5 (4) 3 (3)c
Depression history
 Episodes, median (IQR) 10 (6–20) 10 (6–17.5)
 Age of impairment, years, mean (SD) 21.7 (9.0) 23.1 (9.8)
 Duration of illness, years, median (IQR) 19 (10–30) 18 (10–31)
 Hospital admissions, yes, n (%) 63 (43) 41 (41)
Mania history
 Episodes, median (IQR) 10 (4–20) 9 (4–15)
 Age of impairment, years, mean (SD) 27.2 (11.4) 28.7 (11.7)
 Duration of illness, years, median (IQR) 13 (6–25) 12 (6–26)
 Hospital admissions, yes, n (%) 46 (32) 33 (33)
 Alcohol use, yes, n (%) 109 (86) 71 (85)c
 Smoker, yes, n (%) 80 (56) 54 (55)c
Episode-free run-in period characteristics
 Number of prompts, mean (SD) 9 (1.1) 22.2 (2)
 Percentage of missing values, mean (SD) 10 (14) 13 (14)
 ASRM score across participants
  Mean score, mean (SD) 2.0 (1.6) 1.8 (1.4)
  Standard deviation of score, mean (SD) 1.7 (1.0) 1.6 (0.9)
 QIDS score across participants
  Mean score, mean (SD) 6.2 (2.7) 5.1 (2.4)
  Standard deviation of score, mean (SD) 2.5 (1.2) 2.5 (1.0)
  1. n number of observed values, SD standard deviation, IQR interquartile range
  2. aShort run-in period cohort is the cohort for the main analysis defined by an episode-free run-in period 8 weeks long
  3. bLong run-in period cohort is the cohort for secondary analysis defined by an episode-free run-in period 20 weeks long
  4. cPercentages calculated over the total observed values