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Table 3 Shewhart’s control rules sensitivity and PPV for predicting depressive episodes within the next 4 weeks

From: Control charts for monitoring mood stability as a predictor of severe episodes in patients with bipolar disorder

 

Depressive episodes

Episodes preceded by any rule activation

Rules activated

Rules followed by an episode

n

n

Sensitivity % (95% CI)

n

n

PPV % (95% CI)

Universal X-bar charts

 Short run-in period cohort

  Original dataa

67a

22a

33 (22, 46)a

395a

34a

9 (6, 12)a

  LVCF imputed data

67

27

40 (29, 53)

777

51

7 (5, 9)

 Long run-in period cohort

  Original data

32

11

34 (19, 53)

456

19

4 (3, 7)

  LVCF imputed data

32

11

34 (19, 53)

924

20

2 (1, 3)

Personalized X-bar charts

 Short run-in period cohort

  Original data

67

12

18 (10, 30)

520

21

4 (3, 6)

  LVCF imputed data

67

15

22 (13, 53)

848

33

4 (3, 5)

 Long run-in period cohort

  Original data

32

11

34 (19, 53)

430

26

6 (4, 9)

  LVCF imputed data

32

10

31 (17, 50)

749

27

4 (2, 5)

Individual-moving range charts

 Short run-in period cohort

  Original data

   Individual chart

67

13

19 (11, 31)

785

26

3 (2, 5)

  Moving range chart

67

38

57 (44, 69)

3790

119

3 (3, 4)

  LVCF imputed data

   Individual chart

67

17

25 (16, 38)

1222

42

3 (3, 5)

   Moving range chart

67

44

66 (53, 77)

5170

160

3 (3, 4)

 Long run-in period cohort

  Original data

   Individual chart

32

12

38 (22, 56)

749

30

4 (3, 6)

   Moving range chart

32

22

69 (50, 83)

3246

61

2 (1, 2)

  LVCF imputed data

   Individual chart

32

12

38 (22, 56)

1170

33

3 (2, 4)

   Moving range chart

32

23

72 (53, 86)

4451

75

2 (1, 2)

  1. PPV positive predictive value, CI confidence interval, LVCF last value carried forward
  2. aResults from the main analysis