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Table 4 Difference (95% confidence interval) between main and secondary analysis results over non-imputed data

From: Control charts for monitoring mood stability as a predictor of severe episodes in patients with bipolar disorder

  Non-imputed ASRM Non-imputed QIDS
Sensitivity PPV Sensitivity PPV
Universal X-bar charts
 Short run-in period (main analysis) 0 (0, 0) 0 (0, 0) 0 (0, 0) 0 (0, 0)
 Long run-in period 25.8 (− 0.2, 51.8) − 2.6 (− 5.6, 0.5) 1.5 (− 20.0, 23.0) − 4.4 (− 8.0, − 0.9)
Personalized X-bar charts
 Short run-in period − 1.9 (− 21.1, 17.3) − 2.3 (− 5.2, 0.7) − 14.9 (− 30.9, 1.1) − 4.6 (− 8.0, − 1.1)
 Long run-in period 9.8 (− 16.0, 35.6) − 3.0 (− 6.2, 0.1) 1.5 (− 20.0, 23.0) − 2.6 (− 6.4, 1.3)
Individual-moving range charts
 Short run-in period cohort
  Individual chart 1.9 (− 17.6, 21.4) − 2.9 (− 5.7, − 0.1) − 13.4 (− 29.6, 2.8) − 5.3 (− 8.5, − 2.1)
  Moving range chart 11.3 (− 8.7, 31.3) − 2.9 (− 5.6, − 0.2) 53.7 (39.7, 67.8) − 5.5 (− 8.4, − 2.5)
 Long run-in period cohort
  Individual chart 9.8 (− 16.0, 35.6) − 3.0 (− 5.9, − 0.1) 4.7 (− 17.8, 27.2) − 4.6 (− 7.9, − 1.3)
  Moving range chart 21.8 (− 4.3, 47.9) − 4.1 (− 6.8, − 1.4) 35.9 (14.0, 57.8) − 6.7 (− 9.7, − 3.8)
  1. Numbers in this table can be interpreted as difference of proportions (proportion in the secondary analysis minus proportion in the main analysis) and its corresponding 95% confidence interval. A negative value indicates that the result observed in the secondary analysis was smaller than in the main analysis
  2. ASRM Altman Self-Rating Mania Scale, QIDS Quick Inventory of Depressive Symptomatology—Self-Report, PPV positive predictive value