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Table 1 Aspects covered in the questionnaire on monitoring of patients using lithium

From: Monitoring of patients treated with lithium for bipolar disorder: an international survey


Item number

Items of question

Lithium serum level monitoring


Target values for: acute manic episode in adults (18–60 years old), maintenance treatment in adults, acute manic episode in elderly patients (> 60 years old), maintenance treatment in elderly

Frequency of monitoring lithium serum levels during the first month, months 2–6 and per year

Monitoring of physical and laboratory parameters


Assessment of the following monitoring parameters before, during the first 6 months and during maintenance treatment

Physical parameters: bodyweight, body mass index (BMI), blood pressure, pulse, waist circumference, electrocardiogram (ECG), pregnancy test, 24 h urine examination

Laboratory parameters: creatinine, urea, albumin, glomerular filtration rate (GFR), thyroid stimulating hormone (TSH), parathyroid hormone (PTH), thyroxine (T4), alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT), bilirubin, sodium, potassium, calcium, full blood count, leukocytes, leukocyte differentiation, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (vLDL), triglycerides, fasting glucose

Local system for ensuring monitoring


Reasons to and not to monitor, assessment usage of guidelines or institutional protocols, responsible health care professional for monitoring, usage of laboratory protocols, method of inviting patients for monitoring

Background information


Gender, age, profession, institution of employment, years of lithium prescribing, country