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Table 2 Change in clinical stability indicators during the AOM 400 maintenance phase

From: Aripiprazole once-monthly as maintenance treatment for bipolar I disorder: a 52-week, multicenter, open-label study

Mean (SD) change from baseline to last visit (up to week 52; LOCF)
Assessment De novo Rollover Total
N Result N Result N Result
YMRS total score 377 − 0.33 (3.87) 85 − 0.16 (4.42) 462 − 0.30 (3.97)
MADRS total score 377 1.36 (6.93) 85 0.67 (3.16) 462 1.24 (6.41)
CGI-BP-S overall score 353 0.13 (1.20) 84 − 0.01 (0.69) 437 0.10 (1.12)
CGI-BP-S mania score 353 − 0.07 (0.83) 84 − 0.08 (0.71) 437 − 0.07 (0.81)
CGI-BP-S depression score 353 0.18 (1.14) 84 0.12 (0.52) 437 0.17 (1.05)
  1. AOM 400 aripiprazole once-monthly 400 mg, CGI-BP-S Clinical Global Impressions for Bipolar Disorder-Severity of Illness Scale, LOCF last observation carried forward, MADRS MontgomeryAsberg Depression Rating Scale, SD standard deviation, YMRS Young Mania Rating Scale