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Table 2 Change in clinical stability indicators during the AOM 400 maintenance phase

From: Aripiprazole once-monthly as maintenance treatment for bipolar I disorder: a 52-week, multicenter, open-label study

Mean (SD) change from baseline to last visit (up to week 52; LOCF)

Assessment

De novo

Rollover

Total

N

Result

N

Result

N

Result

YMRS total score

377

− 0.33 (3.87)

85

− 0.16 (4.42)

462

− 0.30 (3.97)

MADRS total score

377

1.36 (6.93)

85

0.67 (3.16)

462

1.24 (6.41)

CGI-BP-S overall score

353

0.13 (1.20)

84

− 0.01 (0.69)

437

0.10 (1.12)

CGI-BP-S mania score

353

− 0.07 (0.83)

84

− 0.08 (0.71)

437

− 0.07 (0.81)

CGI-BP-S depression score

353

0.18 (1.14)

84

0.12 (0.52)

437

0.17 (1.05)

  1. AOM 400 aripiprazole once-monthly 400 mg, CGI-BP-S Clinical Global Impressions for Bipolar Disorder-Severity of Illness Scale, LOCF last observation carried forward, MADRS MontgomeryAsberg Depression Rating Scale, SD standard deviation, YMRS Young Mania Rating Scale