|
Mean (SD) change from baseline to last visit (up to week 52; LOCF)
|
|---|
|
Assessment
|
De novo
|
Rollover
|
Total
|
|---|
|
N
|
Result
|
N
|
Result
|
N
|
Result
|
|---|
|
YMRS total score
|
377
|
− 0.33 (3.87)
|
85
|
− 0.16 (4.42)
|
462
|
− 0.30 (3.97)
|
|
MADRS total score
|
377
|
1.36 (6.93)
|
85
|
0.67 (3.16)
|
462
|
1.24 (6.41)
|
|
CGI-BP-S overall score
|
353
|
0.13 (1.20)
|
84
|
− 0.01 (0.69)
|
437
|
0.10 (1.12)
|
|
CGI-BP-S mania score
|
353
|
− 0.07 (0.83)
|
84
|
− 0.08 (0.71)
|
437
|
− 0.07 (0.81)
|
|
CGI-BP-S depression score
|
353
|
0.18 (1.14)
|
84
|
0.12 (0.52)
|
437
|
0.17 (1.05)
|
- AOM 400 aripiprazole once-monthly 400 mg, CGI-BP-S Clinical Global Impressions for Bipolar Disorder-Severity of Illness Scale, LOCF last observation carried forward, MADRS Montgomery–Asberg Depression Rating Scale, SD standard deviation, YMRS Young Mania Rating Scale
