|
ROI
|
CON
|
SCZ
|
PBD
|
NPBD
|
F(3,156) (p value)
|
---|
Frontal
|
1. Frontal pole
|
2.736
|
2.675
|
2.650
|
2.696
|
1.279 (0.284)
|
2. Superior fontal
|
2.697
|
2.645
|
2.723
|
2.753
|
6.281 (< 0.001)
|
3. Rostral middle frontal
|
2.284
|
2.302
|
2.320
|
2.355
|
2.239 (0.062)
|
4. Caudal middle frontal
|
2.569
|
2.516
|
2.564
|
2.577
|
3.091 (0.029)
|
5. Pars opercularis
|
2.612
|
2.590
|
2.599
|
2.645
|
1.660 (0.178)
|
6. Pars triangularis
|
2.483
|
2.456
|
2.454
|
2.447
|
0.353 (0.787)
|
7. Pars orbitalis
|
2.654
|
2.607
|
2.601
|
2.618
|
1.254 (0.292)
|
8. Precentral
|
2.447
|
2.529
|
2.591
|
2.558
|
4.490 (0.005)
|
9. Paracentral
|
2.431
|
2.369
|
2.464
|
2.458
|
7.764 (< 0.001)
|
10. Lateral orbitofrontal
|
2.537
|
2.519
|
2.503
|
2.584
|
2.274 (0.082)
|
11. Medial orbitofrontal
|
2.327
|
2.308
|
2.330
|
2.395
|
2.019 (0.114)
|
Parietal
|
12. Superior parietal
|
2.276
|
2.209
|
2.225
|
2.259
|
2.153 (0.096)
|
13. Inferior parietal
|
2.516
|
2.437
|
2.488
|
2.526
|
5.136 (0.002)
|
14. Supramarginal
|
2.585
|
2.522
|
2.569
|
2.575
|
4.586 (0.004)
|
15. Postcentral
|
2.110
|
2.107
|
2.089
|
2.074
|
0.512 (0.675)
|
16. Precuneus
|
2.447
|
2.388
|
2.395
|
2.455
|
2.569 (0.062)
|
Temporal
|
17. Temporal pole
|
3.670
|
3.618
|
3.751
|
3.810
|
3.095 (0.029)
|
18. Superior temporal
|
2.868
|
2.817
|
2.827
|
2.854
|
2.676 (0.049)
|
19. Middle temporal
|
2.937
|
2.839
|
2.867
|
2.909
|
3.841 (0.011)
|
20. Inferior temporal
|
2.819
|
2.710
|
2.756
|
2.767
|
4.029 (0.009)
|
21. Bank Sup. Temp. Sulcus
|
2.627
|
2.566
|
2.542
|
2.568
|
1.438 (0.234)
|
22. Fusiform
|
2.744
|
2.663
|
2.726
|
2.778
|
7.476 (< 0.001)
|
23. Transverse temporal
|
2.520
|
2.488
|
2.462
|
2.494
|
2.351 (0.074)
|
24. Parahippocampal
|
2.808
|
2.718
|
2.770
|
2.795
|
2.740 (0.045)
|
25. Entorhinal
|
3.428
|
3.359
|
3.534
|
3.521
|
3.486 (0.017)
|
Occipital
|
26. Lateral occipital
|
2.242
|
2.171
|
2.184
|
2.193
|
2.274 (0.082)
|
27. Lingual
|
2.097
|
2.053
|
2.019
|
2.030
|
0.852 (0.467)
|
28. Cuneus
|
1.928
|
1.889
|
1.878
|
1.917
|
1.799 (0.150)
|
29. Pericalcarine
|
1.725
|
1.703
|
1.734
|
1.618
|
0.446 (0.721)
|
Cingulate
|
30. Rostral Ant. cingulate
|
2.776
|
2.777
|
2.851
|
2.856
|
2.501 (0.062)
|
31. Caudal Ant. cingulate
|
2.525
|
2.554
|
2.560
|
2.568
|
6.441 (< 0.001)
|
32. Posterior cingulate
|
2.508
|
2.468
|
2.499
|
2.615
|
7.062 (< 0.001)
|
33. Isthmus of cingulate
|
2.439
|
2.409
|
2.419
|
2.482
|
1.321 (0.270)
|
Insula
|
34. Insula
|
3.050
|
3.001
|
3.054
|
3.049
|
3.858 (0.011)
|
- Values indicate estimated means of subject groups, controlled for age, sex, race and total intracranial volume. Significance values are uncorrected for multiple comparisons. Italicized regions were significant after Bonferroni correcting for 34 comparisons
- ROI region of interest, CON control, SCZ schizophrenia, PBD psychotic bipolar disorder, NPBD non-psychotic, bipolar disorder, Temp. temporal, Sup. superior, Ant. anterior