Table 1 Factors associated with aggressive behaviors in 216 first-episode BD-I patient-subjects: bivariable logistic regression
From: Aggression among 216 patients with a first-psychotic episode of bipolar I disorder
Factor | Overall, N (%) or mean (SD) | Aggressive behaviors, N (%) or mean (SD) | Statistica | p-value | |
|---|---|---|---|---|---|
Present | Absent | ||||
Subjects | 216 (100.0) | 23 (10.6) | 193 (89.4) | – | – |
Suicide attempt | 30 (13.9) | 7 (30.4) | 23 (11.9) | 4.81 | 0.03 |
Male | 117 (54.2) | 16 (69.6) | 101 (52.3) | 2.54 | 0.11 |
Onset age | 31.2 (13.1) | 35.0 (16.2) | 30.8 (12.6) | 1.95 | 0.16 |
Onset type | |||||
Acute | 131 (60.7) | 13 (56.5) | 118 (61.1) | 0.18 | 0.67 |
Subacute | 72 (33.3) | 8 (34.8) | 64 (33.2) | 0.02 | 0.88 |
Gradual | 13 (6.02) | 2 (8.70) | 11 (5.70) | 0.29 | 0.59 |
Diagnosis at intake | 5.81 | 0.02 | |||
Manic | 134 (62.0) | 15 (65.2) | 119 (61.7) | ||
Mixed | 73 (33.8) | 5 (21.7) | 68 (35.2) | ||
Depressed | 5 (2.31) | 1 (4.35) | 4 (2.07) | ||
Psychosis NOS | 2 (0.93) | 1 (4.35) | 1 (0.52) | ||
Brief psychosis | 1 (0.46) | 0 (0.00) | 1 (0.52) | ||
Schizophreniform | 1 (0.46) | 1 (4.35) | 0 (0.00) | ||
BPRS | |||||
Total score | 77.4 (23.0) | 70.7 (21.2) | 78.3 (23.2) | 2.24 | 0.13 |
Hostility score | 2.46 (1.52) | 2.95 (1.66) | 2.40 (1.50) | 2.38 | 0.12 |
Substance abuse | |||||
Any | 143 (66.2) | 19 (82.6) | 124 (64.3) | 3.42 | 0.06 |
Alcohol | 133 (61.6) | 19 (82.6) | 114 (59.1) | 5.33 | 0.02 |
Drug | 81 (37.5) | 9 (39.1) | 72 (37.3) | 0.03 | 0.86 |
Personality disorderb | 20 (9.26) | 2 (8.70) | 18 (9.33) | 0.01 | 0.92 |
Learning disability | 19 (8.80) | 5 (21.7) | 14 (7.25) | 4.14 | 0.04 |
Follow-up | |||||
Remission (days) | 93.2 (139.5) | 74.2 (77.6) | 95.3 (144.7) | 0.47 | 0.49 |
Relapse (days) | 513.3 (507.4) | 542.3 (389.3) | 510.3 (519.3) | 0.04 | 0.85 |
Functioning (years/n) | 58 (27.6) | 7 (12.1) | 51 (87.9) | 0.28 | 0.59 |