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Table 3 Individual components of the metabolic syndrome and insulin resistance in patients with bipolar disorder (BD) and their unaffected first-degree relatives (UR) compared with healthy individuals (HC)

From: Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives

  BD1 UR2 HC3 P-value
N 206 50 109  
Waist circumference (cm) 85 [78–94] 79 [74–89] 82 [75–90] 0.0081−3
0.42−3
Triglycerides (mmol/L) 0.94 [0.70–1.39] 0.77 [0.66–1.03] 0.76 [0.61–0.97] < 0.0011−3
0.42−3
HDL cholesterol (mmol/L) 1.49 [1.24–1.83] 1.52 [1.29–1.79] 1.68 [1.35–1.94] 0.0011−3
0.0172−3
Systolic blood pressure (mmHg) 120 [111–129] 124 [114–135] 124 [116–136] 0.0041−3
0.92−3
Diastolic blood pressure (mmHg) 77 [70–83] 78 [70–84] 77 [72–85] 0.11−3
0.32−3
Fasting plasma glucose (mmol/L) 5.0 [4.8–5.4] 5.1 [4.8–5.4] 5.0 [4.7–5.2] 0.0471−3
0.12−3
Type 2 diabetes 2 (0.9) 0 0  
Insulin (pmol/L) 55.8 [39.7–84.8] 56.8 [42.0–69.9] 48.9 [38.5–63.6] 0.0091−3
0.12−3
  1. HDL high density lipoprotein, MmHg millimeters of mercury. Continuous variables are presented as median [interquartile range]