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International Journal of Bipolar Disorders
Fig. 3 | International Journal of Bipolar Disorders

Fig. 3

From: Epigenetic markers in inflammation-related genes associated with mood disorder: a cross-sectional and longitudinal study in high-risk offspring of bipolar parents

Fig. 3

Log NR3C1 methylation percentage by study group from the longitudinal model between Time 1 and tIme 2. Estimated longitudinal profiles of log NR3C1 methylation rates. After adjustment, there was evidence that the rate of decrease in controls (green) is steeper than the rate of decrease of unaffected HR (blue) (p = 0.0025, t-value = − 3.20), and affected HR (red) (p = 0.0019, t-value = − 3.30). There was no evidence that the change over time in affected HR (red) was different from unaffected HR (blue) (p = 0.6897, t-value = 0.40)

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