Treatments | Subjects (n) | Responders/subjects (%) | RR [95%CI] | |
---|---|---|---|---|
Drug | Placebo | |||
Anticonvulsants [10 trials, 3 agents] | 1281 |
313/657 [47.6%] |
181/624 [29.0%] |
1.61 [1.39–1.87] |
Antidepressants [12 trials, 11 agents] | 1895 |
383/803 [48.9%] |
419/1092 [38.4%] |
1.32 [1.07–1.62] |
Antipsychotics [13 trials, 6 agents] | 6044 |
2135/3859 [55.3%] |
904/2185 [41.4%] |
1.28 [1.09–1.51] |
Lithium [1 trial, 1 agent] | 265 |
85/136 [62.5%] |
72/129 [55.8%] |
1.12 [0.92–1.37] |
Pooled/totals [36 trials, 21 agents] | 9485 |
2926/5455 [54.4%] |
1576/4030 [39.4%] |
1.37 [1.30–1.44] |