International Journal of Bipolar Disorders

Table 1 Sample demographic and clinical characteristics

From: The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder

	Baseline (n = 96)	1-year follow-up (n = 95)	p-value
Sex
Female	50	50
Age, mean ± SD	45.2 ± 12.4	46.17 ± 12.4
Duration of illness, mean ± SD	13.52 ± 11.8	14.66 ± 11.8
DSM-IV diagnosis
BD-I	79	78
BD-II	17	17
Medication
Combo therapy	81	75
Monotherapy	14	16
No meds	1	4
Childhood trauma (yes)	48	48
LEQ scores, mean ± SD
Bad events	10.2 ± 13.8	6.3 ± 6.6	0.004^b
Good events	9.7 ± 10.2	8.4 ± 7.6	0.191^b
Total events	19.9 ± 18.4	14.1 ± 10.7	0.001^b
Symptom ratings
GAF, mean ± SD	61.5 ± 12.6	65.8 ± 12.4	0.032^a
YMRS sum, mean ± SD	3.9 ± 5.8	2.4 ± 3.7	0.216^b
IDS-C₃₀, mean ± SD	13.7 ± 11.0	10.6 ± 9.7	0.124^b
PANSS sum, mean ± SD	42.8 ± 11.8	39.2 ± 9.6	0.063^b

^aPaired sample t-test
^bWilcoxon signed rank test

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