Table 1 Key inclusion and exclusion criteria for study participants of the risk groups I–III

Risk group I (RG I)

• Age: 15 to 35 years

• Consultation of an early recognition centre/facility

• Presence of at least one of the proposed risk factors for BD:

– Family history of BD

– (Sub)threshold affective symptomatology/depressive syndrome

– Hypomanic/mood swings

– Disturbances of circadian rhythm/sleep other clinical hints

• Diagnosis of: BD, schizoaffective disorder, schizophrenia

• Diagnosis of anxiety, obsessive–compulsive or substance dependence disorder that fully explains the whole symptomatology

• Limited ability to comprehend the study

• Implied expressed negative declaration of intent to participate in the study by a minor and

• Acute suicidality

Risk group II (RG II)

• Age: 15 to 35 years

• In- or outpatients with a depressive syndrome in the context of:

– Major depressive disorder

– Dysthymic disorder

– Cyclothymic disorder

– Minor depressive disorder

– Recurrent brief depressive disorder

– Adjustment disorder with depressed mood

– Depressive disorder Not Otherwise Specified (NOS)

Risk group III (RG III)

• Age: 15 to 35 years

• In- or outpatients with a clinically confirmed ADHD diagnosis