Table 1 Participant & family demographic and clinical characteristics at recruitment
|  | Immediate arm, n = 14 | Delayed arm, n = 13 | Total, n = 27 |
|---|---|---|---|
Age in years: mean (sd) | 16.2 (1.3) | 16.1 (1.5) | 16.1 (1.4) |
Index of Multiple Deprivation: mean (sd) | 23.4 (14.8) | 23.2 (11.1) | 23.3 (12.9) |
CGAS rating: mean (sd) | |||
 Current (last 2 weeks) | 84 (7) | 81.4 (5.2) | 82.7 (6.3) |
 Most severe past episode | 25.1 (5) | 22.4 (8.1) | 23.8 (6.8) |
 Highest in prior year | 81 (7) | 81.5 (5) | 81.2 (7) |
Gender: n (%) | |||
 Female | 13 (92.9) | 10 (76.9) | 23 (85.2) |
Ethnicity: n (%) | |||
 White British | 13 (92.9) | 12 (92.3) | 25 (92.6) |
 White other | 0 (0) | 1 (7.7) | 1 (3.7) |
 Mixed | 1 (7.1) | 0 (0) | 1 (3.7) |
Type of bipolar disorder: n (%) | |||
 Bipolar I | 8 (57.1) | 7 (53.8) | 15 (55.6) |
 Bipolar II | 6 (42.9) | 5 (38.5) | 11 (40.7) |
 Bipolar NOS | 0 (0) | 1 (7.7) | 1 (3.7) |
Comorbid disorders | |||
 GAD | 0 (0) | 2 (15.4) | 2 (7.4) |
 ASD | 2 (14.3) | 2 (15.4) | 4 (14.8) |
 ADHD | 1 (7.1) | 0 (0) | 1 (3.7) |
 ASD + ADHD | 1 (7.1) | 0 (0) | 1 (3.7) |
 Substance abuse or dependence disorder (past 3 months) | 0 (0) | 0 (0) | 0 (0) |
Mood episodes | |||
 Age of diagnosis of BD in years mean (sd) | 12.8 (1.6) | 12.9 (1.3) | 12.8 (1.4) |
Hypomania | |||
 Number of participants n (%) | 8 (57.1) | 8 (61.5) | 16 (59.3) |
 Number of episodes mean (sd) | 3 (1.1) | 2.9 (2) | 3 (1) |
 Lifetime duration in weeks mean (sd) | 7.8 (4.4) | 8.6 (4.5) | 8.1 (4.3) |
 Admissions to hospital | 0 (0) | 0 (0) | 0 (0) |
Mania | |||
 Number of participants n (%) | 8 (57.1) | 7 (53.8) | 15 (55.6) |
 Number of episodes mean (sd) | 2.9 (0.8) | 2.7 (0.8) | 2.8 (0.8) |
 Lifetime duration in weeks mean (sd) | 13.4 (5.2) | 14 (5.3) | 13.7 (5.1) |
 Number of participants experiencing psychotic episodes n (%) | 5 (35.7) | 4 (30.1) | 9 (33.3) |
 Admissions to hospital n (%) | 4 (30.1) | 3 (23.1) | 7 (25.9) |
Depression | |||
 Number of participants n (%) | 14 (100) | 13 (100) | 27 (100) |
 Number of episodes mean (sd) | 4.2 (1.1) | 4.2 (1.1) | 4.2 (1.1) |
 Lifetime duration in weeks mean (sd) | 37.2 (16.9) | 35.9 (16.2) | 36.6 (16.5) |
 Number of participants experiencing psychotic episodes n (%) | 10 (71.4) | 9 (69.2) | 19 (70.4) |
 Admissions to hospital n (%) | 7 (50) | 6 (46.2) | 13 (48.1) |
Medication treatments at trial entry | |||
 Mood stabilizer | 5 (35.7) | 5 (38.5) | 10 (37) |
 Antipsychotic | 8 (57.1) | 10 (76.9) | 18 (66.7) |
 Other | 1 (7.1) | 0 (0) | 1 (3.7) |
 None | 4 (28.6) | 0 (0) | 4 (14.8) |
Family medical history (first degree relatives) | |||
 Bipolar disorder | 5 (35.7) | 4 (30.8) | 9 (33.3) |
 Depression | 4 (28.6) | 10 (76.9) | 14 (51.9) |
 Anxiety | 2 (14.3) | 1 (7.7) | 3 (11.1) |
 ADHD | 2 (14.3) | 3 (23.1) | 5 (18.5) |
 ASD | 2 (14.3) | 2 (15.4) | 4 (14.8) |
 Physical illness | 1 (7.1) | 0 (0) | 1 (3.7) |
 Other | 2 (14.3) | 3 (23.1) | 5 (18.5) |