BD, The MONARCA I trial, n = 33 | BD, The MONARCA I & II trials, n = 117 | HC, n = 40 | p-value* | |
---|---|---|---|---|
Age, years | 29.1 (7.5) | 30.9 (9.9) | 35.2 (12.8) | 0.028 |
Female gender, % (n) | 65.7 (22) | 73 (62.4) | 55 (22) | 0.0063 |
Full time employed, % (n) | 14.3 (5) | 17.1 (20) | 57.5 (23) | < 0.0001 |
PSS scorea | 18.32 (9.22) | 16.30 (8.81) | 6.87 (5.04) | < 0.0001 |
CPFQ scoreb | 21.36 (6.74) | – | – | – |
WHOQoL scorec | 81.58 (13.41) | 86.76 (13.01) | 97.79 (7.37) | < 0.0001 |
FAST scored | 23.22 (16.65) | 21.04 (14.68) | 1.61 (2.10) | < 0.0001 |
SCIP scoree | 73.80 (11.32) | – | – | – |
HDRS, follow-upf | 9.23 (7.27) | 8.77 (7.13) | 0.25 (0.54) | < 0.0001 |
YMRS, follow-upg | 3.14 (4.37) | 3.07 (4.32) | 0.071 (0.27) | < 0.0001 |