Skip to main content

Table 1 Comparison of BCN participants in the US and Europe

From: 25 Years of the International Bipolar Collaborative Network (BCN)

Clinical characteristics

United States (N = 676)

Europe (N = 292)

Early onset (< 19 y)

69.2%***

32.3%

Delay to first treatment for depression (age of onset < 19 y)

13.1 y*

8.4 y

Delay to first treatment for mania (age of onset < 19 y)

11.3y***

5.8y

Prospective nonresponders

51.7%***

31.1%

Life time history of

  

 Anxiety disorder

46.6%***

28.1%

 Alcohol abuse

33.1%***

14.7%

 Substance Abuse

38.3%***

17.8%

 Rapid Cycling

74.1%***

41.5%

 > 20 Episodes

59.0%***

23.3%

 Hospitalizations

Fewer**

More

  1. Burden of illness appears significantly higher in the US subjects (*p < 0.05; **p < 0.01; ***p =  < 0.001)