From: 25 Years of the International Bipolar Collaborative Network (BCN)
Clinical characteristics | United States (N = 676) | Europe (N = 292) |
---|---|---|
Early onset (< 19 y) | 69.2%*** | 32.3% |
Delay to first treatment for depression (age of onset < 19 y) | 13.1 y* | 8.4 y |
Delay to first treatment for mania (age of onset < 19 y) | 11.3y*** | 5.8y |
Prospective nonresponders | 51.7%*** | 31.1% |
Life time history of | Â | Â |
 Anxiety disorder | 46.6%*** | 28.1% |
 Alcohol abuse | 33.1%*** | 14.7% |
 Substance Abuse | 38.3%*** | 17.8% |
 Rapid Cycling | 74.1%*** | 41.5% |
 > 20 Episodes | 59.0%*** | 23.3% |
 Hospitalizations | Fewer** | More |