Patients, n | 373 |
---|---|
Total visits | 849 |
Sex | |
Male, n (%) | 128 (34%) |
Female, n (%) | 245 (66%) |
Bipolar subtype | |
BD I, n (%) | 120 (32%) |
BD II, n (%) | 253 (68%) |
Years of education, median (IQR) | 15 (13–17) |
No. of previous hospitalizations/admissions, median (IQR) | 0 (0–1) |
Family history of BDa, n (%) | 56 (16%) |
Age (years), median (IQR) | 32 (27–40) |
Age at onset (years)b, median (IQR) | 18 (15–22) |
Age at first hypomanic/manic episode (years)c, median (IQR) | 21 (17–27) |
Illness duration (years)d, median (IQR) | 10 (6–16) |
Delay in diagnosis (years)e, median (IQR) | 5 (2–11) |
Follow up time in study (months), median (IQR) | 41 (26–50) |
Follow up time in study (years), median (IQR) | 3 (2–4) |
No. of visits contributed per patient, median (IQR) | 2 (1–3) |
YMRS total score, median (IQR) | 3 (0–6) |
Modified YMRS total scoref, median (IQR) | 1 (0–4) |
No. of patients fulfilling a depressed visit through follow up (Hamilton ≥ 15), n (%) | 135 (36%) |
No. of patients fulfilling a visit with DSM-IV criterion A for hypomania/mania through follow up, n (%) | 127 (34%) |
No. of patients fulfilling a visit with DSM-5 criterion A for hypomania/mania through follow up, n (%) | 63 (17%) |
Baseline visits (first visit by each subject), n | 373 |
YMRS total score at first visit, median (IQR) | 3 (0–6) |
Modified YMRS total score at first visit, median (IQR) | 1 (0–4) |
No. of patients fulfilling DSM-IV criterion A for hypomania/mania at baseline, n (%) | 86 (23%) |
No. of patients fulfilling DSM-5 criterion A for hypomania/mania at baseline, n (%) | 33 (9%) |
YMRS total score for participants fulfilling DSM-IV criterion A at first visits, median (IQR) | 10 (7–14) |
Modified YMRS total score for participants fulfilling DSM-IV criterion A at first visits, median (IQR) | 5 (2–8) |
YMRS total score for participants fulfilling DSM-5 criterion A at first visits, median (IQR) | 14 (10–16) |
Modified YMRS total score for participants fulfilling DSM-5 criterion A at first visits, median (IQR) | 8 (4–10) |
No. of patients with a depressive episode at first visit (Hamilton ≥ 15) at baseline, n (%) | 101 (27%) |