Total visits
|
849
|
Sex
| |
Male, n (%)
|
128 (34%)
|
Female, n (%)
|
245 (66%)
|
Bipolar subtype
| |
BD I, n (%)
|
120 (32%)
|
BD II, n (%)
|
253 (68%)
|
Years of education, median (IQR)
|
15 (13–17)
|
No. of previous hospitalizations/admissions, median (IQR)
|
0 (0–1)
|
Family history of BDa, n (%)
|
56 (16%)
|
Age (years), median (IQR)
|
32 (27–40)
|
Age at onset (years)b, median (IQR)
|
18 (15–22)
|
Age at first hypomanic/manic episode (years)c, median (IQR)
|
21 (17–27)
|
Illness duration (years)d, median (IQR)
|
10 (6–16)
|
Delay in diagnosis (years)e, median (IQR)
|
5 (2–11)
|
Follow up time in study (months), median (IQR)
|
41 (26–50)
|
Follow up time in study (years), median (IQR)
|
3 (2–4)
|
No. of visits contributed per patient, median (IQR)
|
2 (1–3)
|
YMRS total score, median (IQR)
|
3 (0–6)
|
Modified YMRS total scoref, median (IQR)
|
1 (0–4)
|
No. of patients fulfilling a depressed visit through follow up (Hamilton ≥ 15), n (%)
|
135 (36%)
|
No. of patients fulfilling a visit with DSM-IV criterion A for hypomania/mania through follow up, n (%)
|
127 (34%)
|
No. of patients fulfilling a visit with DSM-5 criterion A for hypomania/mania through follow up, n (%)
|
63 (17%)
|
Baseline visits (first visit by each subject), n
|
373
|
YMRS total score at first visit, median (IQR)
|
3 (0–6)
|
Modified YMRS total score at first visit, median (IQR)
|
1 (0–4)
|
No. of patients fulfilling DSM-IV criterion A for hypomania/mania at baseline, n (%)
|
86 (23%)
|
No. of patients fulfilling DSM-5 criterion A for hypomania/mania at baseline, n (%)
|
33 (9%)
|
YMRS total score for participants fulfilling DSM-IV criterion A at first visits, median (IQR)
|
10 (7–14)
|
Modified YMRS total score for participants fulfilling DSM-IV criterion A at first visits, median (IQR)
|
5 (2–8)
|
YMRS total score for participants fulfilling DSM-5 criterion A at first visits, median (IQR)
|
14 (10–16)
|
Modified YMRS total score for participants fulfilling DSM-5 criterion A at first visits, median (IQR)
|
8 (4–10)
|
No. of patients with a depressive episode at first visit (Hamilton ≥ 15) at baseline, n (%)
|
101 (27%)
|