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International Journal of Bipolar Disorders

Table 2 Sociodemographic and clinical characteristics

From: Impact of modification to DSM-5 criterion A for hypomania/mania in newly diagnosed bipolar patients: findings from the prospective BIO study

Patients, n 373
Total visits 849
Sex  
 Male, n (%) 128 (34%)
 Female, n (%) 245 (66%)
Bipolar subtype  
 BD I, n (%) 120 (32%)
 BD II, n (%) 253 (68%)
Years of education, median (IQR) 15 (13–17)
No. of previous hospitalizations/admissions, median (IQR) 0 (0–1)
Family history of BDa, n (%) 56 (16%)
Age (years), median (IQR) 32 (27–40)
Age at onset (years)b, median (IQR) 18 (15–22)
Age at first hypomanic/manic episode (years)c, median (IQR) 21 (17–27)
Illness duration (years)d, median (IQR) 10 (6–16)
Delay in diagnosis (years)e, median (IQR) 5 (2–11)
Follow up time in study (months), median (IQR) 41 (26–50)
Follow up time in study (years), median (IQR) 3 (2–4)
No. of visits contributed per patient, median (IQR) 2 (1–3)
YMRS total score, median (IQR) 3 (0–6)
Modified YMRS total scoref, median (IQR) 1 (0–4)
No. of patients fulfilling a depressed visit through follow up (Hamilton ≥ 15), n (%) 135 (36%)
No. of patients fulfilling a visit with DSM-IV criterion A for hypomania/mania through follow up, n (%) 127 (34%)
No. of patients fulfilling a visit with DSM-5 criterion A for hypomania/mania through follow up, n (%) 63 (17%)
Baseline visits (first visit by each subject), n 373
YMRS total score at first visit, median (IQR) 3 (0–6)
Modified YMRS total score at first visit, median (IQR) 1 (0–4)
No. of patients fulfilling DSM-IV criterion A for hypomania/mania at baseline, n (%) 86 (23%)
No. of patients fulfilling DSM-5 criterion A for hypomania/mania at baseline, n (%) 33 (9%)
YMRS total score for participants fulfilling DSM-IV criterion A at first visits, median (IQR) 10 (7–14)
Modified YMRS total score for participants fulfilling DSM-IV criterion A at first visits, median (IQR) 5 (2–8)
YMRS total score for participants fulfilling DSM-5 criterion A at first visits, median (IQR) 14 (10–16)
Modified YMRS total score for participants fulfilling DSM-5 criterion A at first visits, median (IQR) 8 (4–10)
No. of patients with a depressive episode at first visit (Hamilton ≥ 15) at baseline, n (%) 101 (27%)
  1. aFamily history of BD: Mother, father or sibling with bipolar disorder
  2. bAge at onset: From birthdate to first episode of depression, mania, hypomania or mixed episode
  3. cAge at first hypomanic/manic episode: From birthdate to first mania, hypomania or mixed episode
  4. dIllness duration: From first episode (depression, mania, hypomania or mixed episode) to date of inclusion
  5. eDelay in diagnosis: From the time where the first mania, hypomania or mixed episode occurred to date of the diagnosis of a single manic or mixed episode or a diagnosis of BD
  6. fModified YMRS total score = total score minus item 1, item 2 and item 5
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