| | |
OR
|
95% confidence limits
|
Range of scalea
|
|---|
|
Item 1 (Mood)
|
Unadjusted
|
1.6
|
(1.4, 2.0)
|
0–4
|
| |
Adjustedb
|
1.1
|
(0.8, 1.4)
| |
|
Item 2 (Energy/activity)
|
Unadjusted
|
1.6
|
(1.4, 2.0)
|
0–4
|
| |
Adjusted
|
1.1
|
(0.8, 1.4)
| |
|
Item 3 (Sexual interest)
|
Unadjusted
|
1.6
|
(1.3, 2.1)
|
0–3
|
| |
Adjusted
|
1.2
|
(0.9, 1.6)
| |
|
Item 4 (Sleep)
|
Unadjusted
|
1.6
|
(1.3, 2.0)
|
0–4
|
| |
Adjusted
|
1.3
|
(1.0, 1.6)
| |
|
Item 5 (Irritability)
|
X
|
x
|
x
|
0–6
|
|
Item 6 (Speech)
|
Unadjusted
|
1.4
|
(1.2, 1.5)
|
0–6
|
| |
Adjusted
|
1.1
|
(0.9, 1.2)
| |
|
Item 7 (Language-Thought Disorder)
|
Unadjusted
|
1.8
|
(1.6, 2.2)
|
0–4
|
| |
Adjusted
|
1.5*
|
(1.3, 1.9)*
| |
|
Item 8 (Content)
|
Unadjusted
|
1.5
|
(1.3, 1.8)
|
0–8
|
| |
Adjusted
|
1.0
|
(0.8, 1.3)
| |
|
Item 9 (Aggression)
|
Unadjusted
|
2.5
|
(1.4, 4.5)
|
0–5
|
| |
Adjusted
|
2.2
|
(1.1, 4.2)
| |
|
Item 10 (Appearance)
|
Unadjusted
|
2.4
|
(1.3, 4.6)
|
0–4
|
| |
Adjusted
|
1.2
|
(0.6, 2.6)
| |
|
Item 11 (Insight)
|
Unadjusted
|
1.2
|
(0.8, 1.9)
|
0–6
|
| |
Adjusted
|
0.7
|
(0.4, 1.3)
| |
- Outcome irritability > 0 vs irritability = 0
- aRange of scale: observed minimum and maximum values of the individual YMRS items in data set
- bAdjusted model is adjusted for all the remaining YMRS items: Item 1, Item 2, item 3, item 4, item 6, item 7, item 8, item 9, item 10, item 11
- *Remained statistically significant after adjustment and Bonferroni correction for multiple testing (p < 0.005)
