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International Journal of Bipolar Disorders

Table 3 Cox proportional-hazards model examining effect of bipolar diagnosis on the time-to-first response

From: The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry

Effect

Hazard ratio

95% CI

lower limit

95% CI

upper limit

p-value

VNS + TAU vs TAU

1.6

0.98

2.7

0.06

Bipolar II vs bipolar I

0.96

0.6

1.6

0.9

VNS vs TAU in bipolar I

2.1

1.0

4.3

0.04

VNS vs TAU in bipolar II

1.3

0.6

2.6

0.5

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