Table 1 Baseline characteristics of patients treated in 52 week long-term study
Most recent or current episode of bipolar I disorder | |||
|---|---|---|---|
All Patients (n = 199) | Depressed episode (n = 117) | Non-Depressed episode (n = 82) | |
Demographics and clinical characteristics | |||
Male, n (%) | 102 (51.3) | 63 (53.8) | 39 (47.6) |
Age years, mean (SD) | 41.6 (12.0) | 40.0 (10.9) | 43.8 (13.1) |
Duration of bipolar I disorder, mean years (SD) | 13.5 (11.1) | 13.8 (10.6) | 13.0 (11.7) |
With rapid cycling, n (%) | 30 (15.1) | 15 (12.8) | 15 (18.3) |
Efficacy measure at long-term study baseline | |||
MADRS, mean (SD) | 12.4 (10.3) | 16.0 (10.2) | 7.3 (8.0) |
CGI-BP-S Overall, mean (SD) | 2.98 (1.29) | 3.10 (1.25) | 2.80 (1.33) |
CGI-BP-S Depression, mean (SD) | 2.51 (1.39) | 3.03 (1.31) | 1.77 (1.13) |
CGI-BP-S Mania, mean (SD) | 1.77 (1.18) | 1.23 (0.56) | 2.55 (1.39) |
SDS, mean (SD)# | 11.9 (8.7) | 13.7 (9.03) | 9.2 (7.6) |
YMRS, mean (SD) | 4.7 (6.7) | 2.0 (2.8) | 8.7 (8.6) |
HAM-A, mean (SD) | 8.3 (7.2) | 10.6 (7.5) | 5.0 (5.2) |
Safety measure at long-term study baseline | |||
DIEPSS (excluding overall severity), mean (SD) | 0.36 (0.78) | 0.50 (0.87) | 0.16 (0.60) |