From: Late chronotype predicts more depressive symptoms in bipolar disorder over a 5 year follow-up period
Rate ratio [95% CI] | |||||
---|---|---|---|---|---|
Age (years) | Sex (male) | Baseline score | Early chronotype | Late chronotype | |
PHQ-9 ≥ 5 | 0.995 [0.992–0.997] | 1.069 [0.980- 1.166] | 0.996 [0.990–1.00] | 1.115 [0.977—1.272] | 1.290 [1.135–1.466] |
GAD-7 ≥ 10 | 0.995 [0.992–0.998] | 0.945 [0.854–1.045] | 1.034 [1.024–1.043] | 1.003 [0.871–1.155] | 1.034 [0.903–1.185] |
HAM-D ≥ 10 | 1.002 [0.993–1.012] | 1.162 [0.905–1.492] | 1.084 [1.071–1.098] | 0.826 [0.564–1.210] | 0.794 [0.547–1.151] |
YMRS ≥ 12 | 1.001 [0.985–1.018] | 0.822 [0.525–1.286] | 1.164 [1.133–1.195] | 0.973 [0.485–1.951] | 0.968 [0.486–1.929] |