Skip to main content
International Journal of Bipolar Disorders
Fig. 2 | International Journal of Bipolar Disorders

Fig. 2

From: Using density of antecedent events and trajectory path analysis to investigate family-correlated patterns of onset of bipolar I disorder: a comparison of cohorts from Europe and USA

Fig. 2

Trajectories of evolution of BD-I in probands and parents. In the bubble plot, the size of the bubble represents the proportion of the group who experience a particular disorder, the position of the bubble vertically gives the median AAO, whilst the position on the horizontal axis approximates to the timing of onset of a disorder in the interval between the onset of the first full threshold mental disorder and the onset of the last comorbidity. It is notable that the median AAO of the first mental disorder (specific phobia) is similar in the Proband and Parent subgroups, and that the sequence of onset of disorders (except, e.g. OCD) is similar. The size of the bubbles is somewhat similar, but AAOs of comorbidities begin to occur earlier in the Proband subgroup, and median AAO of BD-I is clearly earlier than in the Parent subgroup. Both curves show the fit for the trajectory curve is less for comorbidities that occur post-onset of BD-I

Back to article page