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Table 2 Characteristics of 184 individuals with BD-I (92 sex-matched proband-parent pairs)

From: Using density of antecedent events and trajectory path analysis to investigate family-correlated patterns of onset of bipolar I disorder: a comparison of cohorts from Europe and USA

 

Cumulative probability

Median age at onset in years (interquartile range)

 

Number

(%)c

Females

100

54.3

  

Age at onset of BD

  

19 (15.3, 26.0)

Duration of BD

  

20.3 (10.3, 35.8)

Lifetime comorbidities:

    

 ≥ 1 comorbid mental disordera

95

51.6

  

Age at onset of first mental disorderb

  

15.0 (10.5, 17.8)

Social phobia

9

5

14.5 (9.0, 20.3)

Specific phobia

14

7.5

9.0 (6.3, 13.8)

Obsessive compulsive disorder

6

3.3

17.5 (11.5, 28.0)

Generalized anxiety disorder

30

16.3

21.8 (17.0, 27.3)

Agoraphobia

12

6.5

17.8 (12.3, 28.0)

Panic disorder

33

18.0

23.0 (15.5, 32.3)

Eating disorder

11

6.0

17 (12.8, 22.5)

Substance use disorder

23

12.5

18.0 (15.8, 25.3)

Alcohol use disorder

58

31.5

28.3 (23.0, 37.5)

  1. aComorbid mental disorder refers to any DSM IV diagnosed disorder that occurred (irrespective of BD-I mood episodes);
  2. bFirst mental disorder refers to a clinical condition that met criteria for a full-threshold DSM IV diagnosis
  3. cDenominator for comorbid disorders ranges from n = 175 to n = 184 (due to small number of sporadic missing values)