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Table 6 Scoring high on YMRS item 2 (Agitation) or/and 5 (Irritability) predicted more severe depression in (hypo)manic subjects

From: Mania and bipolar depression: complementing not opposing poles—a post-hoc analysis of mixed features in manic and hypomanic episodes

YMRS item

IDS-c score for no or low degree of agitation or irritability

IDS-c score for agitated or irritable

p-Value

Agitation (item 2)

20.78

22.38

0.04

Irritability (item 5)

20.47

31.96

 < 0.001

 

IDS-c score for no or low degree of both agitation and irritability

IDS-c score for agitated or irritable

p-Value

Agitation and irritability

20.07

24.12

 < 0.001

 

IDS-c score for no or low degree of both agitation and irritability

IDS-c score for both agitated and irritable

p-Value

Agitation and irritability

20.07

30.05

 < 0.003