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International Journal of Bipolar Disorders

Table 2 Multivariate logistic regression analysis with lifetime suicide attempt as the dependent variable

From: Dissecting the genetic architecture of suicide attempt and repeated attempts in Korean patients with bipolar disorder using polygenic risk scores

  Odds ratio 95% CI P
PRS for suicide attempt as the independent variable
 PRS for suicide attempt 1.32 1.05–1.66 0.018
 Age 0.97 0.95–1.00 0.026
 Sex, female 1.27 0.78–2.07 0.334
 Diagnosis, bipolar II disorder 1.96 1.22–3.16 0.006
 Study center, SNUBH 1.26 0.77–2.07 0.356
 1st principal componenta 0.29 0.00–24.07 0.587
 2nd principal componenta 0.80 0.01–66.14 0.920
PRS for obsessive–compulsive disorder as the independent variable
 PRS for obsessive–compulsive disorder 1.32 1.05–1.66 0.017
 Age 0.98 0.95–1.00 0.028
 Sex, female 1.29 0.79–2.09 0.312
 Diagnosis, bipolar II disorder 1.99 1.24–3.21 0.005
 Study center, SNUBH 1.31 0.80–2.15 0.285
 1st principal componenta 0.18 0.00–15.05 0.448
 2nd principal componenta 0.95 0.01–78.63 0.982
  1. PRS polygenic risk score, SNUBH Seoul National University Bundang Hospital
  2. aFive outlier samples were removed after visual inspection of the multidimensional scaling plots, then the principal components were recalculated
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