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Table 2 Baseline characteristics of sample

From: A pilot trial of quetiapine, lithium, or placebo added to divalproex sodium for hypomanic or manic episodes in ambulatory adults with bipolar I disorder

  Entire cohort
N = 75
DVP + PBO
n = 24
DVP + Li
n = 25
DVP + QTP
n = 26
Significance test
Age at baseline (mean, SD) 35.5 (10.4) 38.8 (11.9) 33.3 (9.1) 34.5 (9.7) F(2) = 1.91, p = 0.155
Women 38 (50.7%) 10 (41.7%) 12 (48.0%) 16 (61.5%) χ2 (2) = 2.08, p = 0.354
Race/ethnicity
 Caucasian 53 (70.7%) 18 (75.0%) 17 (68.0%) 18 (69.2%) χ2 (2) = 0.33, p = 0.848
 Other 22 (29.3%) 6 (25.0%) 8 (32.0%) 8 (30.8%)  
YMRS score at baseline (mean, SD) 22.97 (6.20) 22.92 (5.72) 23.84 (7.49) 22.19 (5.32) F(2) = 0.4449, p = 0.643
Mean HAM-D score at baseline (mean, SD) 13.57 (6.50) 13.88 (6.02) 13.20 (6.81) 13.65 (6.86) F(2) = 0.0673, p = 0.935
Marital status
 Married or cohabitating 25 (33.3%) 7 (29.2%) 8 (32.0%) 10 (38.5%) χ2 (2) = 0.52, p = 0.773
 Single, divorced, widowed or separated 50 (66.7%) 17 (70.8%) 17 (68.0%) 16 (61.5%)  
Education
 High school diploma or less 19 (25.3%) 8 (33.3%) 5 (20.0%) 6 (23.1%) χ2 (4) = 2.91, p = 0.573
 Some college or vocational 33 (44.0%) 8 (33.3%) 11 (44.0%) 14 (53.8%)  
 Associates degree or more 23 (30.7%) 8 (33.3%) 9 (36.0%) 6 (23.1%)  
Employment status
 Self, PT, or FT employment 47 (62.7%) 17 (70.8%) 14 (56.0%) 16 (61.5%) χ2 (2) = 1.17, p = 0.556
 Not employed 28 (37.3%) 7 (29.2%) 11 (44.0%) 10 (38.5%)  
Age at onset of first symptoms of depression 12.5 (6.9) 12.4 (8.0) 13.2 (6.4) 11.8 (6.3) F(2) = 12.99, p = 0.763
Age at onset of first symptoms of mania 15.2 (12.6) 13.4 (10.3) 17.4 (18.4) 14.6 (5.6) F(2) = 0.65, p = 0.524
Mean number of lifetime episodes of depression 3.5 (1.1) 3.4 (1.0) 3.7 (0.9) 3.5 (1.3) F(2) = 0.50, p = 0.607
Mean number of lifetime episodes of mania 3.9 (0.6) 3.9 (0.7) 4 (0.0) 3.8 (0.9) F(2) = 0.39, p = 0.679
Mean number of lifetime episodes of hypomania 4.0 (0.5) 4.1 (0.4) 3.9 (0.6) 4.0 (0.6) F(2) = 1.33, p = 0.272
Age of diagnosis of any mood disorder 26.7 (11.2) 29.5 (11.2) 25.4 (10.2) 25.5 (11.9) F(2) = 1.09, p = 0.342
Number of lifetime psychiatric hospitalizations 1.2 (3.7) 1.7 (6.1) 1.0 (1.7) 1.0 (1.8) F(2) = 0.32, p = 0.725
Self-reported lifetime history of rapid cycling 60 (85.1%) 18 (75.0%) 23 (92.0%) 22 (88.0%) χ2 (2) = 0.40, p = 0.818
Self-reported lifetime history of psychosis 26 (35.1%) 8 (33.3%) 10 (40%) 8 (32%) χ2 (2) = 3.04, p = 0.219
  1. *Significant at p < 0.05