Table 2 Baseline characteristics of sample
Entire cohort N = 75 | DVP + PBO n = 24 | DVP + Li n = 25 | DVP + QTP n = 26 | Significance test | |
|---|---|---|---|---|---|
Age at baseline (mean, SD) | 35.5 (10.4) | 38.8 (11.9) | 33.3 (9.1) | 34.5 (9.7) | F(2) = 1.91, p = 0.155 |
Women | 38 (50.7%) | 10 (41.7%) | 12 (48.0%) | 16 (61.5%) | χ2 (2) = 2.08, p = 0.354 |
Race/ethnicity | |||||
Caucasian | 53 (70.7%) | 18 (75.0%) | 17 (68.0%) | 18 (69.2%) | χ2 (2) = 0.33, p = 0.848 |
Other | 22 (29.3%) | 6 (25.0%) | 8 (32.0%) | 8 (30.8%) | |
YMRS score at baseline (mean, SD) | 22.97 (6.20) | 22.92 (5.72) | 23.84 (7.49) | 22.19 (5.32) | F(2) = 0.4449, p = 0.643 |
Mean HAM-D score at baseline (mean, SD) | 13.57 (6.50) | 13.88 (6.02) | 13.20 (6.81) | 13.65 (6.86) | F(2) = 0.0673, p = 0.935 |
Marital status | |||||
Married or cohabitating | 25 (33.3%) | 7 (29.2%) | 8 (32.0%) | 10 (38.5%) | χ2 (2) = 0.52, p = 0.773 |
Single, divorced, widowed or separated | 50 (66.7%) | 17 (70.8%) | 17 (68.0%) | 16 (61.5%) | |
Education | |||||
High school diploma or less | 19 (25.3%) | 8 (33.3%) | 5 (20.0%) | 6 (23.1%) | χ2 (4) = 2.91, p = 0.573 |
Some college or vocational | 33 (44.0%) | 8 (33.3%) | 11 (44.0%) | 14 (53.8%) | |
Associates degree or more | 23 (30.7%) | 8 (33.3%) | 9 (36.0%) | 6 (23.1%) | |
Employment status | |||||
Self, PT, or FT employment | 47 (62.7%) | 17 (70.8%) | 14 (56.0%) | 16 (61.5%) | χ2 (2) = 1.17, p = 0.556 |
Not employed | 28 (37.3%) | 7 (29.2%) | 11 (44.0%) | 10 (38.5%) | |
Age at onset of first symptoms of depression | 12.5 (6.9) | 12.4 (8.0) | 13.2 (6.4) | 11.8 (6.3) | F(2) = 12.99, p = 0.763 |
Age at onset of first symptoms of mania | 15.2 (12.6) | 13.4 (10.3) | 17.4 (18.4) | 14.6 (5.6) | F(2) = 0.65, p = 0.524 |
Mean number of lifetime episodes of depression | 3.5 (1.1) | 3.4 (1.0) | 3.7 (0.9) | 3.5 (1.3) | F(2) = 0.50, p = 0.607 |
Mean number of lifetime episodes of mania | 3.9 (0.6) | 3.9 (0.7) | 4 (0.0) | 3.8 (0.9) | F(2) = 0.39, p = 0.679 |
Mean number of lifetime episodes of hypomania | 4.0 (0.5) | 4.1 (0.4) | 3.9 (0.6) | 4.0 (0.6) | F(2) = 1.33, p = 0.272 |
Age of diagnosis of any mood disorder | 26.7 (11.2) | 29.5 (11.2) | 25.4 (10.2) | 25.5 (11.9) | F(2) = 1.09, p = 0.342 |
Number of lifetime psychiatric hospitalizations | 1.2 (3.7) | 1.7 (6.1) | 1.0 (1.7) | 1.0 (1.8) | F(2) = 0.32, p = 0.725 |
Self-reported lifetime history of rapid cycling | 60 (85.1%) | 18 (75.0%) | 23 (92.0%) | 22 (88.0%) | χ2 (2) = 0.40, p = 0.818 |
Self-reported lifetime history of psychosis | 26 (35.1%) | 8 (33.3%) | 10 (40%) | 8 (32%) | χ2 (2) = 3.04, p = 0.219 |