Entire cohort N = 75 | DVP + PBO n = 24 | DVP + Li n = 25 | DVP + QTP n = 26 | |
---|---|---|---|---|
Average number of side effects reported | 5.4 (2.6) | 6.5 (2.2) | 4.5 (2.4) | 5.4 (3.0) |
Increased appetite | 34 (45.3%) | 11 (14.7%) | 12 (16%) | 11 (14.7%) |
Sedation | 32 (42.7%) | 9 (12%) | 2 (2.7%) | 21 (28%) |
Dry mouth | 29 (38.7%) | 6 (8%) | 8 (10.7%) | 15 (20%) |
Nausea | 25 (33.3%) | 8 (10.7%) | 9 (12%) | 8 (10.7%) |
Tiredness | 23 (30.7%) | 7 (9.3%) | 4 (5.3%) | 12 (16%) |
Increased thirst | 21 (28%) | 2 (2.7%) | 7 (9.3%) | 12 (16%) |
Upset stomach | 21 (28%) | 8 (10.7%) | 7 (9.3%) | 6 (8%) |
Diarrhea | 20 (26.7%) | 9 (12%) | 7 (9.3%) | 4 (5.3%) |
Gastrointestinal problems | 18 (24%) | 7 (9.3%) | 8 (10.7%) | 3 (4%) |
Increased urinary frequency | 16 (21.3%) | 3 (4%) | 9 (12%) | 4 (5.3%) |
Word finding difficulties | 14 (18.7%) | 1 (1.3%) | 6 (8%) | 7 (9.3%) |
Slurred speech | 10 (13.3%) | 0 (0%) | 3 (4%) | 7 (9.3%) |
Ataxia* | 10 (13.3%) | 0 (0%) | 3 (4%) | 7 (9.3%) |
Weakness | 9 (12%) | 2 (2.7%) | 2 (2.7%) | 5 (6.7%) |
Dizzy/lightheaded | 9 (12%) | 0 (0%) | 2 (2.7%) | 7 (9.3%) |
Edema | 9 (12%) | 3 (4%) | 2 (2.7%) | 4 (5.3%) |
Impaired memory | 9 (12%) | 1 (1.3%) | 3 (4%) | 5 (6.7%) |
Feeling dull | 9 (12%) | 0 (0%) | 2 (2.7%) | 7 (9.3%) |
Cognitive slowing | 9 (12%) | 0 (0%) | 2 (2.7%) | 7 (9.3%) |
Joint/muscle aches | 9 (12%) | 4 (5.3%) | 2 (2.7%) | 3 (4%) |
Tactile sensations | 7 (9.3%) | 1 (1.3%) | 1 (1.3%) | 5 (6.7%) |
Increased appetite | 34 (45.3%) | 11 (14.7%) | 12 (16%) | 11 (14.7%) |