Using decision-analysis modelling to estimate the economic impact of the identification of unrecognised bipolar disorder in primary care: the untapped potential of screening

International Journal of Bipolar Disorders

Table 3 Delta Study algorithm and MDQ performance comparison at respective optimal cut-off points

Tool	Cut-off	Optimisation	Sensitivity	Specificity	PPV	NPV	Total per-person costs	Misdiagnoses (Y5)
Delta study	0.46	Misdiagnoses	0.87	0.81	0.46	0.97	$ 49,513	260
Delta study	0.56	Costs	0.76	0.87	0.52	0.95	$ 49,462	282
MDQ	$\ge$11	Costs & misdiagnoses	0.56	0.92	0.58	0.91	$ 49,717	367

PPV: Positive predictive value; NPV: Negative predictive value; Y5: Year 5 of followup; MDQ: Mood disorder questionnaire