Skip to main content

Table 1 Bipolar 1 vs. 2 subjects: characteristics

From: Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept

Measure

Measure or Percentage [95%CI]

RR

p-value

BD-1

BD-2

(BD-1/BD-2)

[t or χ2]

Subjects (n)

657

720

1/1.10

Sex (%)

0.06 [3.66]

Women

54.3 [50.4–58.2]

59.4 [55.8–63.1]

1/1.09

Men

45.7 [41.8–49.6]

40.6 [36.9–44.2]

1.13

Family history (%)

Mood disorders

60.2 [55.8–64.4]

68.4 [64.4–72.2]

1/1.14

0.005 [8.04]

Bipolar disorder

32.6 [28.6–36.8]

30.8 [27.1–34.9]

1.06

0.54 [0.38]

Suicide

9.12 [6.85–11.9]

8.81 [6.69–11.3]

1.04

0.85 [0.04]

Ages or durations (years)

First symptoms

22.4 [21.0–23.8]

27.6 [25.7–29.4]

1/1.23

 < 0.0001 [4.24]

Syndromal onset

25.6 [24.8–26.4]

30.3 [29.3–31.4]

1/1.18

 < 0.0001 [7.03]

First diagnosis

27.4 [26.0–28.8]

33.7 [31.8–35.6]

1/1.23

 < 0.0001 [5.04]

First treatment

27.9 [26.6–29.2]

33.5 [32.0–35.1]

1/1.20

 < 0.0001 [5.09]

Symptoms to treatment

5.72 [4.50–6.95]

6.86 [5.67–8.04]

1/1.20

0.19 [1.30]

First suicide attempt

33.2 [31.0–35.4]

36.9 [34.1–39.7]

1/1.11

0.04 [2.07]

Illness duration

17.1 [15.9–18.1]

18.1 [17.1–19.1]

1/1.06

0.17 [1.38]

Current age

43.2 [42.0–44.4]

48.4 [47.2–49.6]

1/1.12

 < 0.0001 [6.09]

Socioeconomic status (%)

Educated > high school

19.7 [16.5–23.1]

28.3 [24.8–32.01]

1/1.44

0.0004 [12.4]

Unemployeda

16.5 [13.7–19.7]

9.01 [6.96–11.4]

1.83

 < 0.0001 [16.7]

Low SES rankingb

17.9 [13.7–22.8]

5.32 [3.23–8.19]

3.36

 < 0.0001 [18.8]

Marital history

    

Ever married (%)c

38.8 [35.0–42.6]

53.2 [49.4–57.0]

1/1.37

 < 0.0001 [28.5]

Ever separated (%)

17.9 [13.9–22.6]

14.7 [11.6–18.4]

1.22

0.24 [1.41]

Children (n/person)

0.80 [0.70–0.90]

1.10 [1.00–1.21]

1/1.38

 < 0.0001 [4.11]

Temperament scores

Anxious

1.14 [0.95–1.33]

1.36 [1.21–1.51]

1/1.19

0.07 [1.80]

Cyclothymic

5.21 [4.69–5.73]

6.06 [5.64–6.48]

1/1.16

0.01 [2.49]

Dysthymic

3.15 [2.81–3.49]

3.49 [3.21–3.77]

1/1.11

0.13 [1.51]

Hyperthymic

3.55 [3.20–3.90]

3.65 [2.78–4.52]

1/1.03

0.66 [0.44]

Irritable

1.84 [1.55–2.13]

1.85 [1.59–2.11]

1/1.01

0.98 [0.03]

Bodyweight

    

BMI (kg/m2)

25.0 [24.5–25.5]

24.3 [23.8–247]

1.03

0.04 [2.06]

Obese (%)d

21.7 [15.9–28.4]

10.7 [6.35–16.6]

2.03

0.007 [7.37]

  1. a. Employed status: employed, students, housewives, and retirees; b. less than one salary of approximately 1,000 euros/month for a family of four; c. married, divorced, widowed; d. BMI≥30